David L. Smith is Professor of Global Health at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. Professor Smith studied Ecology and Evolutionary Biology at Princeton University with Professor Simon A. Levin before moving into epidemiology and global health. Prof. Smith’s scientific research has been on the ecology, epidemiology, and evolution of infectious diseases. Prof. Smith has published extensively on the epidemiology, dynamics, and control of malaria, influenza, cholera, rabies, Staphylococcus aureus, and nosocomial pathogens; the evolution of resistance to antibiotics in nosocomial pathogens; the evolution of resistance to antimalarial drugs; malaria elimination and eradication; and the bioeconomics of infectious diseases. Prof. Smith was one of the original members of the Malaria Atlas Project, which has published evidence-based global maps of Plasmodium falciparum and P. vivax.
At IHME, Prof. Smith works closely with the local burden of disease team. His interests have expanded to include policy interventions to reduce all causes of mortality in children under 5. A key interest has been to develop analytical tools to compare simple and abstract compartment models to exquisitely detailed individual-based models. Those tools could be used to determine which kinds of models (or modeling processes) tend to produce the most robust policy assessments. This research supports the translation of the output of sophisticated Bayesian geostatistical analysis – particularly the estimates of spatial uncertainty – into usable advice about how, where, and when to distribute interventions.
Golding N, Burstein R, Longbottom J, Browne AJ, Fullman N, Osgood-Zimmerman A, Earl L, Bhatt S, Cameron E, Casey DC, Dwyer-Lindgren L, Farag TH, Flaxman AD, Fraser MS, Gething PW, Gibson HS, Graetz N, Krause LK, Kulikoff XR, Lim SS, Mappin B, Morozoff C, Reiner RC Jr, Sliger A, Smith DL, Wang H, Weiss DJ, Murray CJL, Moyes CL, Hay SI. Mapping under-5 and neonatal mortality in Africa, 2000–15: a baseline analysis for the Sustainable Development Goals. The Lancet
GBD 2016 Mortality Collaborators. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1084–1150.
GBD 2016 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1151–210.
GBD 2016 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1260-344.
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390; 1211–59.
GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1345-1422.
GBD 2016 SDG Collaborators. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. The Lancet. 12 Sept 2017: 390; 1423–59.
Gething PW, Casey DC, Weiss DJ, Bisanzio D, Bhatt S, Cameron E, Battle KE, Dalrymple U, Rozier J, Rao PC, Kutz MJ, Barber RM, Huynh C, Shackelford KA, Coates MM, Nguyen G, Fraser MS, Kulikoff R, Wang H, Naghavi M, Smith DL, Murray CJL, Hay SI, Lim SS. Mapping Plasmodium falciparum Mortality in Africa between 1990 and 2015. The New England Journal of Medicine. 2016 Oct 10. DOI: 10.1056/NEJMoa1606701
Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle KE, Moyes CL, Henry A, Eckhoff PA, Wenger EA, Briët O, Penny MA, Smith TA, Bennett A, Yukich J, Eisele TP, Griffin JT, Fergus CA, Lynch M, Lindgren F, Cohen JM, Murray CJL, Smith DL, Hay SI, Cibulskis RE, Gething PW. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015 Oct 8; 526:207–211. doi: 10.1038/nature15535.
Pigott DM, Golding N, Mylne A, Huang Z, Henry AJ, Weiss DJ, Brady OJ, Kraemer MUG, Smith DL, Moyes CL, Bhatt S, Gething PW, Horby PW, Bogoch II, Brownstein JS, Mekaru SR, Tatem AJ, Khan K, Hay SI. Mapping the zoonotic niche of Ebola virus disease in Africa. eLife. 2014 Sep 8; 3:e04395. doi: 10.7554/eLife.04395.