Identifying subnational regions with the highest burden and mapping associated risk factors can aid in reducing preventable childhood diarrhoea.
April 20, 2020
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
We show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units.
January 8, 2020
Despite remarkable declines over the study period, many low- and middle-income countries remain far from the ambitious World Health Organization Global Nutrition Targets to reduce stunting by 40% and wasting to less than 5% by 2025. Large disparities in prevalence and progress exist across and within countries; our maps identify high-prevalence areas even within nations otherwise succeeding in reducing overall child growth failure prevalence. By highlighting where the highest-need populations reside, these geospatial estimates can support policy-makers in planning interventions that are adapted locally and in efficiently directing resources towards reducing CGF and its health implications.
December 30, 2019
Travel time to health facilities in areas of outbreak potential: maps for guiding local preparedness and response
Here, we use travel time to link facilities and populations at risk of viral hemorrhagic fevers (VHFs) and identify spatial variation in these respective preparedness demands.
December 25, 2019
Educational attainment is an important social determinant of maternal, newborn, and child health. Here we expand on the available precision SDG evidence by estimating the subnational distribution of educational attainment, including the proportions of individuals who have completed key levels of schooling, across all low- and middle-income countries from 2000 to 2017.
October 16, 2019
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations.
September 30, 2019
Identifying residual hotspots and mapping lower respiratory infection morbidity and mortality in African children from 2000 to 2017
Lower respiratory infections (LRIs) are the leading cause of death in children under the age of 5, despite the existence of vaccines against many of their aetiologies.
July 22, 2019
Our estimates provide the ability to visualize subnational exclusive breastfeeding variability and identify populations in need of additional breastfeeding support.
June 19, 2019
Mapping the global prevalence, incidence, and mortality of Plasmodium falciparum, 2000–17: a spatial and temporal modelling study
Since 2000, the scale-up of malaria control interventions has substantially reduced morbidity and mortality caused by the disease globally, fuelling bold aims for disease elimination. High-resolution maps of P. falciparum provide a contemporary resource for informing global policy and malaria control planning, program implementation, and monitoring initiatives.
June 19, 2019
Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000–17: a spatial and temporal modelling study
Plasmodium vivax exacts a significant toll on health worldwide, yet few efforts to date have quantified the extent and temporal trends of its global distribution. This study presents the first global maps of P. vivax clinical burden from 2000 to 2017.
June 10, 2019
This study is the first to consider the spread of Aedes mosquito vectors to project dengue suitability. Our projections provide a key missing piece of evidence for the changing global threat of vector-borne disease and will help decision-makers worldwide to better prepare for and respond to future changes in dengue risk.
May 22, 2019
The onchocerciasis database can be used to by the global health community to advance understanding of the distribution of onchocerciasis infection and disease.
May 15, 2019
Our analysis reveals substantial within-country variation in the prevalence of HIV throughout sub-Saharan Africa and local differences in both the direction and rate of change in HIV prevalence between 2000 and 2017, highlighting the degree to which important local differences are masked when examining trends at the country level.
April 5, 2019
Mapping diphtheria-pertussis-tetanus vaccine coverage in Africa, 2000–2016: a spatial and temporal modeling study
Routine childhood vaccination is among the most cost-effective, successful public health interventions available. Amid substantial investments to expand vaccine delivery throughout Africa and strengthen administrative reporting systems, most countries still require robust measures of local routine vaccine coverage and changes in geographical inequalities over time.
March 26, 2019
Utilizing general human movement models to predict the spread of emerging infectious diseases in resource-poor settings
Human mobility is an important driver of geographic spread of infectious pathogens. Our findings show that transmission patterns derived from general human movement models can improve forecasts of spatiotemporal transmission patterns in places where local mobility data is unavailable.
March 26, 2019
Geographical distribution and prevalence of podoconiosis in Rwanda: a cross-sectional country-wide survey
Podoconiosis is a type of tropical lymphoedema that causes massive swelling of the lower limbs. The disease is associated with both economic insecurity, due to long-term morbidity-related loss of productivity, and intense social stigma. Reliable and detailed data on the prevalence and distribution of podoconiosis are scarce. We aimed to fill this data gap by doing a nationwide community-based study to estimate the number of cases throughout Rwanda.
March 5, 2019
The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births
In 2015, high rates of microcephaly were reported in Northeast Brazil following the first South American Zika virus (ZIKV) outbreak. Reported microcephaly rates in other Zika-affected areas were significantly lower, suggesting alternate causes or the involvement of arboviral cofactors in exacerbating microcephaly rates. This study strengthens the evidence that congenital ZIKV infection, particularly in the first 2 trimesters of pregnancy, is associated with microcephaly and less frequently with other birth defects.
March 4, 2019
The global population at risk from mosquito-borne diseases – including dengue, yellow fever, chikungunya, and Zika – is expanding in concert with changes in the distribution of two key vectors: Aedes aegypti and Aedes albopictus. Our maps and predictions offer an opportunity to strategically target surveillance and control programs and thereby augment efforts to reduce arbovirus burden in human populations globally.
October 30, 2018
Global variation in bacterial strains that cause tuberculosis disease: a systematic review and meta-analysis
The host, microbial, and environmental factors that contribute to variation in tuberculosis (TB) disease are incompletely understood. This study provides the most comprehensive systematic analysis of the evidence for diversity in bacterial strains that cause TB disease. The results show both geographic and epidemiological differences between strains, which could inform our understanding of the global burden of TB.
September 19, 2018
Diarrheal diseases are the third leading cause of disease and death in children younger than 5 years of age in Africa and were responsible for an estimated 30 million cases of severe diarrhea and 330,000 deaths in 2015. Our findings showed concentrated areas of diarrheal disease and diarrhea-related death in countries that had a consistently high burden as well as in countries that had considerable national-level reductions in diarrhea burden.