Global Burden of Disease 2019 disease, injury, and impairment summaries
These two-page summaries offer a concise overview of causes, impairments, and risk factors modeled in GBD and the health loss related to them. The summaries include a summary results statement; a definition of the disease, injury, impairment, or risk; and a brief listing of modeling updates in GBD 2019 compared to previous GBD rounds. Tables and figures display metrics for each topic. Please use the menus below to select your topic of interest. To learn more about what the summaries include, please visit these pages:
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Suggested citation: Institute for Health Metrics and Evaluation (IHME). GBD 2019 Cause and Risk Summary: [CAUSE/RISK/IMPAIRMENT NAME]. Accessed [INSERT DATE]). Seattle, USA: IHME, University of Washington, 2020.
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Summary In 2019, ambient particulate matter pollution was the leading Level 4 risk factor for DALYs among environmental and occupational risks. It contributed to 118 million (95% UI 95·9–138) DALYs and 4·14 million (3·45–4·80) deaths in 2019. Definition Ambient particulate matter pollution is the...Read more
Summary Amphetamine use disorders resulted in 1·40 million (95% UI 0·954–2·04) global DALYs in 2019 and were responsible for 0·1% (0·0–0·1) of total global DALYs. Definition Amphetamine dependence is a substance-related disorder involving a dysfunctional pattern of amphetamine use. Included in the...Read more
Summary Globally, there were 1·76 billion (95% UI 1·74–1·78) prevalent cases of anaemia in 2019, up from 1·44 billion (1·43–1·45) in 1990. Anaemia caused 50·3 million (33·4–73·4) YLDs in 2019. The largest causes were dietary iron deficiency, thalassaemia and sickle cell trait, and malaria...Read more
Summary Animal contact (venomous and non-venomous) caused 93 500 deaths (95% UI 61 900–114 000) in 2019. 67·7% (58·2–72·2) of global deaths occurred in south Asia. Age-standardised death rates decreased by 15·9% (-25·6 to -1·8) between 2010 and 2019. Definition Animal contact includes deaths and...Read more
Summary Anorexia nervosa (AN) resulted in 0·85 million (95% UI 0·51–1·32) global DALYs in 2019. AN contributed to 0·7% (0·5–1·0) of DALYs for the aggregate of mental disorders. Definition AN is an eating disorder incorporating deaths and disability from refusal to maintain minimally normal body...Read more
Summary Anxiety disorders resulted in 28·7 million (95% UI 19·9–39·3) global DALYs in 2019, equivalent to 1·1% (0·8–1·5) of DALYs. Anxiety disorders contributed to 22·9% (18·6–27·5) of DALYs for the aggregate of mental disorders. Definition Anxiety disorders incorporate disability caused by...Read more
Summary Aortic aneurysm was responsible for 3·32 million (95% UI 3·11–3·52) YLLs in 2019. There were 172 000 (157 000–183 000) deaths due to aortic aneurysms in 2019, an 82·1% (67·3–97·0) increase from 1990. Non-fatal burden is not currently estimated for aortic aneurysm. Definition Aortic...Read more
Summary 17·7 million (95% UI 14·1–22·3) cases of appendicitis occurred in 2019, resulting in 33 400 deaths (27 300–38 100) and 1·50 million (1·24–1·71) global DALYs. Definition This Level 3 cause incorporates death and disability resulting from an inflammation of the appendix. Total sources...Read more
Summary Asbestosis was responsible for 59 700 YLLs (95% UI 43 700–69 300) and 11 500 YLDs (7710–16 700) in 2019. Asbestosis accounted for 7·8% (5·9–9·3) of total overall pneumoconiosis DALYs in 2019. Definition Asbestosis is a lung disease caused by long-term inhalation of asbestos particles...Read more
Summary The global burden of ascariasis in 2019 was 754 000 DALYs (95% UI 479 000–1 140 000) and a total of 2090 deaths (1640–2640). Definition Ascariasis is a helminthic disease caused by the parasitic roundworm Ascaris lumbricoides . Diagnosis is made by examination of stool, with or without...Read more