Remarkable financial and political efforts have been focused on the reduction of child mortality during the past few decades. Timely measurements of levels and trends in under-5 mortality are important to assess progress towards the Millennium Development Goal 4 (MDG 4) target of reduction of child mortality by two-thirds from 1990 to 2015, and to identify models of success.
This chapter introduces key health metrics, as well as data sources and the analytic methods used in their estimation. It also provides examples, at both the global and country level, that illustrate their use to shape policy. The chapter focuses on two health metrics: disability-adjusted life-years (DALYs), which can give policymakers a comprehensive view of overall population health; and effective coverage, which can provide insight into how well health systems are delivering services to the populations who need them.
Tracking development assistance for health for low- and middle-income countries gives policymakers information about spending patterns and potential improvements in resource allocation. We tracked the flows of development assistance and explored the relationship between national income, disease burden, and assistance.
Since the first isolation of dengue virus (DENV) in 1943, four types have been identified. Documenting the type-specific record of DENV spread has important implications for understanding patterns in dengue hyperendemicity and disease severity as well as vaccine design and deployment strategies. Here we summarize the global distribution of confirmed instances of each DENV type from 1943 to 2013 in a series of global maps.
Ischemic Heart Disease (IHD) is the leading cause of death worldwide. The Global Burden of Diseases, Risk Factors and Injuries (GBD) 2010 Study estimated global and regional IHD mortality from 1980 to 2010.
Ischemic heart disease (IHD) burden consists of years of life lost from IHD deaths and years of disability lived with three nonfatal IHD sequelae: nonfatal acute myocardial infarction (AMI), angina pectoris, and ischemic heart failure. Our aim was to estimate global and regional burden of IHD in 1990 and 2010.
The Global Burden of Disease (GBD) 2010 Study has published disability-adjusted life year (DALY) data at both regional and country levels from 1990 to 2010. Concurrently, the Institute for Health Metrics and Evaluation (IHME) has published estimates of development assistance for health (DAH) at the country-disease level for this same period of time.
The Arab world has a set of historical, geopolitical, social, cultural, and economic characteristics and has been involved in several wars that have affected the burden of disease. Moreover, financial and human resources vary widely across the region. We aimed to examine the burden of diseases and injuries in the Arab world for 1990, 2005, and 2010 using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010).
Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but their application is restricted by uncertainty about their reliability.
Tobacco is a leading global disease risk factor. Understanding national trends in prevalence and consumption is critical for prioritizing action and evaluating tobacco control progress.
Sodium intakes exceed the recommended levels in almost all countries with small differences by age and sex. Virtually all populations would benefit from sodium reduction, supported by enhanced surveillance.
Research assessing the relationship between government health expenditure and development assistance for health channeled to governments (DAHG) has not considered that this relationship may depend on whether DAHG is increasing or decreasing. We explore this issue using general method of moments estimation and a panel of financial flows data spanning 119 countries and 16 years.
The objectives of this study were to provide an accurate estimate of antenatal HIV screening and its determinants among pregnant women in El Salvador and help local authorities make informed decisions for targeted interventions around mother-to-child transmission (MTCT).
Lu et al. found that health aid displaces domestically-raised government health expenditure, which renders health aid at least partially fungible. These findings are questioned in The Fungibility of Health Aid Reconsidered. Van de Sijpe’s emphasis on disaggregating on- and off-budget aid is a valid contribution, although his empirical conclusions are overstated.
The Global Burden of Disease (GBD) Study 2010 estimated the GBD attributable to 15 categories of skin disease from 1990 to 2010 for 187 countries.
We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
Depressive disorders were a leading cause of burden in the Global Burden of Disease (GBD) 1990 and 2000 studies. Here, we analyze the burden of depressive disorders in GBD 2010 and present severity proportions, burden by country, region, age, sex, and year, as well as burden of depressive disorders as a risk factor for suicide and ischemic heart disease.
We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) to estimate the global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990—2010.
Previous estimates of mortality in Iraq attributable to the 2003 invasion have been heterogeneous and controversial, and none were produced after 2006. The purpose of this research was to estimate direct and indirect deaths attributable to the war in Iraq between 2003 and 2011.
Previous studies of anemia epidemiology have been geographically limited with little detail about severity or etiology. Using publicly available data, we estimated mild, moderate and severe anemia from 1990 to 2010 for 187 countries, both sexes, and 20 age groups. We then performed cause-specific attribution to 17 conditions using data and resources from the Global Burden of Diseases, Injuries and Risk Factors (GBD) 2010 Study.
Rates of neonatal and maternal mortality are high in Ghana. In-facility delivery and other maternal services could reduce this burden, yet utilization rates of key maternal services are relatively low, especially in rural areas. We tested a theoretical implication that travel time negatively affects the use of in-facility delivery and other maternal services.
No systematic attempts have been made to estimate the global and regional prevalence of amphetamine, cannabis, cocaine, and opioid dependence, and quantify their burden. We aimed to assess the prevalence and burden of drug dependence, as measured in years of life lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life years (DALYs).
Over the last 30 years, HIV/AIDS has emerged as a major global health challenge. Globally, the trend is that non-communicable diseases and injuries are accounting for a larger share of disease burden, but HIV/AIDS is a notable exception. Maintaining and expanding the response to the epidemic will require assessment of its magnitude and impact at the country level. It is also critical to examine the HIV/AIDS epidemic in the context of other health problems to clearly understand its impact and effectively allocate resources.
In 2012, data from GBD 2010 were published, providing results for 1990, 2005, and 2010. Hundreds of collaborators reported summary results for the world and 21 epidemiologic regions, covering 291 diseases and injuries, 1,160 sequelae of these causes, and mortality and burden attributable to 67 risk factors. GBD 2010 addressed a number of major limitations to previous analyses, including strengthening the statistical methods used for estimation and using disability weights derived from surveys of the general population. Metrics produced include leading causes of death, years of life lost, years lived with disability, and disability-adjusted life years (DALYs), which are the years of healthy life lost by a person due to death or disability.