Research Articles

We used data from the Global Burden of Disease 2015 study to calculate the burden of lower respiratory infections in the 22 countries of the Eastern Mediterranean Region from 1990 to 2015. 

We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 to examine the burden of mental disorders in the Eastern Mediterranean Region. 

We aimed to determine the leading causes of premature mortality and disability using disability-adjusted life years (DALYs) and describe the relative burden of disease and injuries in Ethiopia.

Japan has entered the era of super-aging and advanced health transition, which is increasingly putting pressure on the sustainability of its health system. The level and pace of this health transition might vary across regions within Japan and concern is growing about increasing regional variations in disease burden. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) provides a comprehensive, comparable framework. We used data from GBD 2015 with the aim to quantify the burden of disease and injuries, and to attribute risk factors in Japan at a subnational, prefecture level.

In Ethiopia there is no complete registration system to measure disease burden and risk factors accurately. In this study, the 2015 Global Burden of Diseases, Injuries, and Risk Factors (GBD) data were used to analyze the incidence, prevalence, and mortality rates of malaria in Ethiopia over the last 25 years.

The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) provides an up-to-date analysis of the burden of diarrheal diseases. This study assesses cases, deaths, and etiologies spanning the past 25 years and informs the changing picture of diarrheal disease worldwide.

National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (i.e., amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardized cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.

Regional variation in cardiovascular mortality is well-known but county-level estimates for all major cardiovascular conditions have not been produced. 

Examining life expectancy by county allows for tracking geographic disparities over time and assessing factors related to these disparities. This information is potentially useful for policymakers, clinicians, and researchers seeking to reduce disparities and increase longevity.

Adolescence and emerging adulthood form a critical time period for the achievement of optimal health and nutrition across all stages of the life course. The results of this study paint a less than ideal picture of current young people's nutrition, suggesting dual burdens of underweight and high body-mass index in many countries and variable improvements in micronutrient deficiencies across geographical regions. 

In this study, we further explore global health financing trends and examine how the sources of funds used, types of services purchased, and development assistance for health disbursed change with economic development.

Exposure to ambient air pollution increases morbidity and mortality, and is a leading contributor to global disease burden. We explored spatial and temporal trends in mortality and burden of disease attributable to ambient air pollution from 1990 to 2015 at global, regional, and country levels.