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GBD Publications


May 29, 2013
Global burden of oral conditions in 1990-2010: a systematic analysis
Research Article
The Global Burden of Disease (GBD) 2010 study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990.
March 4, 2013
UK health performance: findings of the Global Burden of Disease Study 2010
Research Article
The United Kingdom has provided universal health care and public health programming for more than six decades. To guide future policymaking in the UK, it is important to analyze trends in population health over time. Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010), researchers examined three critical questions: what are the patterns of health loss in the UK, what are the leading preventable risks that explain some of those patterns, and how do UK outcomes compare to a set of comparable countries in the European Union (EU) and elsewhere in 1990 and 2010.
March 4, 2013
The Global Burden of Disease: Generating Evidence, Guiding Policy
Policy Report
The Global Burden of Disease: Generating Evidence, Guiding Policy provides an overview of the reasons why the Global Burden of Disease (GBD) is an essential tool for evidence-based health policymaking and summarizes the main findings of the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010). GBD 2010 is the most comprehensive study of its kind, producing comparative metrics for 291 different causes of premature death and disability across 187 countries, 20 age groups, and both sexes for three time periods: 1990, 2005, and 2010. The study also estimated 67 potentially preventable causes of ill health, or risk factors, such as smoking, high blood pressure, and household air pollution.
December 13, 2012
Healthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
Healthy life expectancy, or HALE, is a measure of average population health summarizing both mortality and non‐fatal outcomes. HALE is used for comparisons of health across countries or for measuring change over time. These comparisons can shed light on key questions about how morbidity worsens or improves as mortality declines.
December 13, 2012
Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010
Research Article
Measurement of the global burden of disease using disability‐adjusted life years (DALYs) requires disability weights that measure health losses for all non‐fatal consequences of disease and injury. There has been vigorous debate over the definition and measurement of these weights. The primary objective was a comprehensive re‐estimation of disability weights through a large‐scale, population‐based, empirical investigation in which judgments about health loss associated with many causes were elicited from the general public in diverse communities. This is a marked improvement over previous efforts, which relied solely upon judgments from a small group of health professionals.
December 13, 2012
Disability‐adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
In this paper, results on years lost due to premature mortality (YLLs) and years lived with disability (YLDs) are combined to examine the overall burden of disease across 291 diseases and injuries by country for the period 1990 to 2010.
December 13, 2012
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
The goal of this research was to estimate deaths and years of lives lost (YLLs) by age, sex, and region for 235 causes at two points in time – 1990 and 2010. This information can be used to better inform global efforts to assess whether society is or is not making progress in reducing the burden of premature – and especially avoidable – mortality.
December 13, 2012
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
The goal of this study is to calculate what proportion of deaths or disability‐adjusted life years (DALYs) can be attributed to specific risk factors, holding other independent factors unchanged. Quantification of the disease burden caused by different risks informs prevention by identifying which risks make the greatest contribution to poor health. No complete revision of global burden of disease caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed changes in burden attributable to risk factors over time.
December 13, 2012
Years lived with disability (YLDs) for 1,160 sequelae of 289 diseases and injuries, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
Individuals, households, and health systems devote enormous resources to curing, preventing, and eliminating non‐fatal, disabling health conditions. Therefore, it is essential that some form of measuring and tracking non‐fatal burdens be available for policy and planning purposes.
December 13, 2012
Age‐specific and sex‐specific mortality in 187 countries, 1970–2010: a systematic analysis for the Global Burden of Disease Study 2010
Research Article
The number of deaths in each age and sex group for countries, regions, and the world is a critical starting point for assessing the Global Burden of Disease (GBD). A careful estimation of deaths and mortality rates by age and sex is essential to assess progress, improve health, and extend the lives of people around the world. Information about mortality rates and causes of death at different ages, especially premature mortality, is also an important impetus for public policy action.
February 2, 2012
Global malaria mortality between 1980 and 2010: a systematic analysis
Research Article
Malaria caused over 1.2 million deaths worldwide in 2010, twice the number found in the most recent comprehensive study of the disease. While malaria is traditionally considered a childhood disease, this study shows that there is a significant disease burden in adults.
February 4, 2011
National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5.4 million participants
Research Article
New research shows that global systolic blood pressure (SBP) has decreased slightly since 1980, but trends varied significantly across regions and countries.
March 31, 2010
The burden of injuries in Iranian children in 2005
Research Article
Research shows that more than 44,000 Iranian children under the age of 15 died due to injuries between 2001 and 2006, making injuries the leading cause of death among children in Iran.

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