Summary 722 000 cases (95% UI 595 000–878 000) of acute glomerulonephritis occurred in 2019, resulting in 10 500 deaths (7200–12 200) and 307 000 global DALYs (204 000–363 000).
Definition This Level 3 cause incorporates death and disability resulting from acute episodes of inflammation and injury to the filtering units of the kidney (glomeruli), generally resulting in haematuria, oedema, and hypertension.
Total sources | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Incidence | 285 | |||||||||||
Prevalence | 0 | |||||||||||
Remission | 0 | |||||||||||
Causes of death | 2841 | |||||||||||
Other | 0 | |||||||||||
Table 1:
Total sources used in GBD 2019 estimation
What is new in GBD 2019?
- •To improve case ascertainment of acute glomerulonephritis, we used hospital and claims data that were adjusted to account for both inpatient and outpatient encounters, rather than inpatient encounters only.
- •Tested new bias adjustment methods with the reference case definition based on published serological, histological, and/or imaging criteria. However, due to insufficient comparison data that is available, we used diagnosis as indicated by ICD code from hospital and claims data as reference.
- •USA claims data were adjusted to other administrative sources using MR-BRT analysis prior to analysis in DisMod-MR, accounting for selection bias among privately insured populations.
- •Modelled excess mortality rate (EMR) in MR-BRT by age and sex as a function of HAQ Index to provide greater guidance to DisMod-MR on expected pattern of EMR.
Prevalence
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Incidence
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Deaths
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YLLs
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YLDs
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DALYs
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Cases
(millions) |
Rate (per 100 000)
|
Cases
(millions) |
Rate (per 100 000)
|
Deaths
(millions) |
Rate (per 100 000)
|
YLLs
(millions) |
Rate (per 100 000)
|
YLDs
(millions) |
Rate (per 100 000)
|
DALYs
(millions) |
Rate (per 100 000)
|
|
2019 | ||||||||||||
Both Sexes | 0·0484 (0·0394 to 0·0583) |
0·6 (0·5 to 0·8) |
0·722 (0·595 to 0·878) |
9·5 (7·7 to 11·5) |
0·0105 (0·00720 to 0·0122) |
0·1 (0·1 to 0·2) |
0·305 (0·201 to 0·359) |
3·9 (2·5 to 4·6) |
0·00245 (0·00145 to 0·00380) |
0·0 (0·0 to 0·0) |
0·307 (0·204 to 0·363) |
3·9 (2·6 to 4·6) |
Females | 0·0226 (0·0183 to 0·0273) |
0·6 (0·5 to 0·7) |
0·337 (0·277 to 0·411) |
8·9 (7·2 to 10·9) |
0·00485 (0·00378 to 0·00598) |
0·1 (0·1 to 0·1) |
0·137 (0·0938 to 0·177) |
3·4 (2·3 to 4·5) |
0·00114 (0·000683 to 0·00177) |
0·0 (0·0 to 0·0) |
0·139 (0·0948 to 0·178) |
3·5 (2·3 to 4·5) |
Males | 0·0258 (0·0210 to 0·0310) |
0·7 (0·5 to 0·8) |
0·385 (0·318 to 0·467) |
10·0 (8·2 to 12·2) |
0·00567 (0·00297 to 0·00685) |
0·2 (0·1 to 0·2) |
0·168 (0·0828 to 0·206) |
4·4 (2·1 to 5·3) |
0·00131 (0·000773 to 0·00202) |
0·0 (0·0 to 0·1) |
0·169 (0·0841 to 0·208) |
4·4 (2·2 to 5·4) |
Percentage change 2010-19 | ||||||||||||
Both Sexes | 8·2% (5·6 to 10·9) |
–1·7% (–3·8 to 0·2) |
8·9% (7·0 to 10·9) |
–1·2% (–2·7 to –0·1) |
–2·2% (–13·6 to 10·4) |
–20·7% (–29·7 to –10·6) |
–17·0% (–26·4 to –5·8) |
–28·7% (–36·7 to –19·3) |
8·2% (5·6 to 10·9) |
–1·7% (–3·8 to 0·2) |
–16·8% (–26·2 to –5·8) |
–28·5% (–36·5 to –19·2) |
Females | 8·4% (5·5 to 10·9) |
–1·6% (–3·9 to 0·3) |
9·0% (7·0 to 11·0) |
–1·1% (–2·5 to 0·0) |
–1·9% (–16·0 to 13·7) |
–21·2% (–32·6 to –8·8) |
–18·8% (–29·9 to –5·3) |
–30·4% (–39·7 to –19·7) |
8·4% (5·5 to 10·9) |
–1·6% (–3·9 to 0·3) |
–18·6% (–29·7 to –5·2) |
–30·3% (–39·5 to –19·6) |
Males | 8·1% (5·4 to 11·3) |
–1·8% (–4·2 to 0·7) |
8·7% (6·7 to 10·8) |
–1·3% (–3·1 to –0·1) |
–2·5% (–19·4 to 15·3) |
–20·4% (–34·3 to –6·4) |
–15·5% (–29·2 to –0·9) |
–27·2% (–39·2 to –15·0) |
8·1% (5·4 to 11·3) |
–1·8% (–4·2 to 0·7) |
–15·3% (–28·9 to –0·8) |
–27·1% (–38·9 to –15·0) |
Numbers in parentheses are 95% uncertainty intervals. |
Table 2:
Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths | YLLs | YLDs | DALYs | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1990 | 115th | 109th | 161st | 150th | ||||||||
2010 | 117th | 119th | 160th | 160th | ||||||||
2019 | 115th | 120th | 158th | 159th | ||||||||
Table 3:
Rank among Level 3 causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined

Figure 1:
Composition of DALYs by YLLs and YLDs for both sexes combined, 2019


Figure 2:
Age-standardised DALY rates for each location by SDI, both sexes combined, 2019

Figure 3:
Composition of DALYs by YLLs and YLDs, age group, and sex, 2019


Figure 4:
Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019