Summary There were 124 000 incident cases (95% UI 109 000–136 000), 94 100 deaths (82 600–101 000), and 3·06 million (2·77–3·37) DALYs due to acute myeloid leukaemia globally in 2019.
Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (specifically acute myeloid leukaemia), including ICD-10 codes such as C92.0.
Total sources | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Incidence | 1066 | |||||||||||
Prevalence | 3 | |||||||||||
Remission | 0 | |||||||||||
Causes of death | 2884 | |||||||||||
Other | 0 | |||||||||||
Table 1:
Total sources used in GBD 2019 estimation
What is new in GBD 2019?
- •New location-years of population-based cancer registry data were added, with a focus on paediatric cancer data.
- •Mortality-to-incidence ratio models included additional data and were modified to perform more smoothing across time and age.
- •Survival estimation was updated to use age-specific rather than all-ages survival curves, impacting age-specific prevalence and YLD estimates.
Prevalence
|
Incidence
|
Deaths
|
YLLs
|
YLDs
|
DALYs
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases
(millions) |
Rate (per 100 000)
|
Cases
(millions) |
Rate (per 100 000)
|
Deaths
(millions) |
Rate (per 100 000)
|
YLLs
(millions) |
Rate (per 100 000)
|
YLDs
(millions) |
Rate (per 100 000)
|
DALYs
(millions) |
Rate (per 100 000)
|
|
2019 | ||||||||||||
Both Sexes | 0·197 (0·173 to 0·221) |
2·5 (2·2 to 2·8) |
0·124 (0·109 to 0·136) |
1·6 (1·4 to 1·7) |
0·0941 (0·0826 to 0·101) |
1·2 (1·0 to 1·3) |
3·02 (2·74 to 3·34) |
38·6 (34·9 to 42·5) |
0·0351 (0·0245 to 0·0462) |
0·4 (0·3 to 0·6) |
3·06 (2·77 to 3·37) |
39·0 (35·2 to 43·1) |
Females | 0·0979 (0·0834 to 0·111) |
2·4 (2·1 to 2·8) |
0·0568 (0·0492 to 0·0635) |
1·4 (1·2 to 1·5) |
0·0410 (0·0344 to 0·0450) |
1·0 (0·8 to 1·1) |
1·32 (1·15 to 1·48) |
33·0 (28·9 to 37·3) |
0·0164 (0·0114 to 0·0220) |
0·4 (0·3 to 0·5) |
1·33 (1·16 to 1·49) |
33·4 (29·2 to 37·7) |
Males | 0·0994 (0·0801 to 0·116) |
2·7 (2·1 to 3·1) |
0·0675 (0·0547 to 0·0767) |
1·8 (1·5 to 2·1) |
0·0531 (0·0437 to 0·0603) |
1·4 (1·2 to 1·6) |
1·71 (1·43 to 2·00) |
44·6 (37·0 to 52·1) |
0·0187 (0·0129 to 0·0250) |
0·5 (0·4 to 0·7) |
1·73 (1·44 to 2·02) |
45·1 (37·5 to 52·8) |
Percentage change 2010-19 | ||||||||||||
Both Sexes | 11·9% (0·9 to 24·0) |
–4·2% (–13·2 to 6·0) |
19·0% (10·1 to 28·5) |
–2·1% (–9·3 to 5·6) |
21·2% (15·3 to 27·5) |
–1·9% (–6·6 to 3·3) |
12·8% (5·2 to 21·3) |
–2·6% (–9·2 to 4·8) |
16·9% (7·7 to 27·2) |
–3·0% (–10·8 to 5·0) |
12·9% (5·2 to 21·4) |
–2·6% (–9·2 to 4·8) |
Females | 9·7% (–3·4 to 23·4) |
–5·6% (–16·9 to 6·5) |
16·8% (6·9 to 27·1) |
–3·7% (–11·8 to 4·9) |
18·6% (11·7 to 26·5) |
–3·6% (–9·4 to 3·2) |
11·1% (1·8 to 21·6) |
–3·9% (–12·2 to 5·6) |
14·6% (4·1 to 25·9) |
–4·5% (–13·3 to 5·4) |
11·1% (1·9 to 21·7) |
–3·9% (–12·1 to 5·5) |
Males | 14·1% (2·0 to 29·1) |
–2·7% (–12·6 to 9·7) |
20·9% (11·2 to 31·9) |
–0·7% (–8·7 to 8·0) |
23·3% (16·6 to 31·2) |
–0·7% (–6·0 to 5·4) |
14·2% (5·9 to 25·6) |
–1·6% (–8·6 to 7·8) |
19·0% (9·2 to 30·9) |
–1·5% (–9·5 to 7·7) |
14·2% (6·0 to 25·7) |
–1·6% (–8·6 to 7·8) |
Numbers in parentheses are 95% uncertainty intervals. |
Table 2:
Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths | YLLs | YLDs | DALYs | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1990 | 114th | 113th | 252nd | 164th | ||||||||
2010 | 101st | 104th | 249th | 149th | ||||||||
2019 | 90th | 98th | 248th | 145th | ||||||||
Table 3:
Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined

Figure 1:
Composition of DALYs by YLLs and YLDs for both sexes combined, 2019

Figure 2:
Percentage of DALYs attributable to top risk factors, for both sexes combined, 2019


Figure 3:
Age-standardised DALY rates for each location by SDI, both sexes combined, 2019

Figure 4:
Composition of DALYs by YLLs and YLDs, age group, and sex, 2019


Figure 5:
Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019