Summary There were 124 000 incident cases (95% UI 109 000–136 000), 94 100 deaths (82 600–101 000), and 3·06 million (2·77–3·37) DALYs due to acute myeloid leukaemia globally in 2019.

Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (specifically acute myeloid leukaemia), including ICD-10 codes such as C92.0.

Total sources
Incidence 1066
Prevalence 3
Remission 0
Causes of death 2884
Other 0
Table 1: Total sources used in GBD 2019 estimation
What is new in GBD 2019?
  • •New location-years of population-based cancer registry data were added, with a focus on paediatric cancer data.
  • •Mortality-to-incidence ratio models included additional data and were modified to perform more smoothing across time and age.
  • •Survival estimation was updated to use age-specific rather than all-ages survival curves, impacting age-specific prevalence and YLD estimates.
Prevalence
Incidence
Deaths
YLLs
YLDs
DALYs
Cases
(millions)
Rate (per 100 000)
Cases
(millions)
Rate (per 100 000)
Deaths
(millions)
Rate (per 100 000)
YLLs
(millions)
Rate (per 100 000)
YLDs
(millions)
Rate (per 100 000)
DALYs
(millions)
Rate (per 100 000)
2019
Both Sexes
0·197
(0·173
to 0·221)
2·5
(2·2
to 2·8)
0·124
(0·109
to 0·136)
1·6
(1·4
to 1·7)
0·0941
(0·0826
to 0·101)
1·2
(1·0
to 1·3)
3·02
(2·74
to 3·34)
38·6
(34·9
to 42·5)
0·0351
(0·0245
to 0·0462)
0·4
(0·3
to 0·6)
3·06
(2·77
to 3·37)
39·0
(35·2
to 43·1)
Females
0·0979
(0·0834
to 0·111)
2·4
(2·1
to 2·8)
0·0568
(0·0492
to 0·0635)
1·4
(1·2
to 1·5)
0·0410
(0·0344
to 0·0450)
1·0
(0·8
to 1·1)
1·32
(1·15
to 1·48)
33·0
(28·9
to 37·3)
0·0164
(0·0114
to 0·0220)
0·4
(0·3
to 0·5)
1·33
(1·16
to 1·49)
33·4
(29·2
to 37·7)
Males
0·0994
(0·0801
to 0·116)
2·7
(2·1
to 3·1)
0·0675
(0·0547
to 0·0767)
1·8
(1·5
to 2·1)
0·0531
(0·0437
to 0·0603)
1·4
(1·2
to 1·6)
1·71
(1·43
to 2·00)
44·6
(37·0
to 52·1)
0·0187
(0·0129
to 0·0250)
0·5
(0·4
to 0·7)
1·73
(1·44
to 2·02)
45·1
(37·5
to 52·8)
Percentage change 2010-19
Both Sexes
11·9%
(0·9
to 24·0)
–4·2%
(–13·2
to 6·0)
19·0%
(10·1
to 28·5)
–2·1%
(–9·3
to 5·6)
21·2%
(15·3
to 27·5)
–1·9%
(–6·6
to 3·3)
12·8%
(5·2
to 21·3)
–2·6%
(–9·2
to 4·8)
16·9%
(7·7
to 27·2)
–3·0%
(–10·8
to 5·0)
12·9%
(5·2
to 21·4)
–2·6%
(–9·2
to 4·8)
Females
9·7%
(–3·4
to 23·4)
–5·6%
(–16·9
to 6·5)
16·8%
(6·9
to 27·1)
–3·7%
(–11·8
to 4·9)
18·6%
(11·7
to 26·5)
–3·6%
(–9·4
to 3·2)
11·1%
(1·8
to 21·6)
–3·9%
(–12·2
to 5·6)
14·6%
(4·1
to 25·9)
–4·5%
(–13·3
to 5·4)
11·1%
(1·9
to 21·7)
–3·9%
(–12·1
to 5·5)
Males
14·1%
(2·0
to 29·1)
–2·7%
(–12·6
to 9·7)
20·9%
(11·2
to 31·9)
–0·7%
(–8·7
to 8·0)
23·3%
(16·6
to 31·2)
–0·7%
(–6·0
to 5·4)
14·2%
(5·9
to 25·6)
–1·6%
(–8·6
to 7·8)
19·0%
(9·2
to 30·9)
–1·5%
(–9·5
to 7·7)
14·2%
(6·0
to 25·7)
–1·6%
(–8·6
to 7·8)
Numbers in parentheses are 95% uncertainty intervals.
Table 2: Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths YLLs YLDs DALYs
1990 114th 113th 252nd 164th
2010 101st 104th 249th 149th
2019 90th 98th 248th 145th
Table 3: Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined
Figure 1: Composition of DALYs by YLLs and YLDs for both sexes combined, 2019
Figure 2: Percentage of DALYs attributable to top risk factors, for both sexes combined, 2019
No Legend
Figure 3: Age-standardised DALY rates for each location by SDI, both sexes combined, 2019
Figure 4: Composition of DALYs by YLLs and YLDs, age group, and sex, 2019
No Legend
Figure 5: Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019