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Chronic kidney disease due to diabetes mellitus type 2 — Level 4 cause


Summary Chronic kidney disease (CKD) due to diabetes type 2 was responsible for 9·87 million (95% UI 8·11–11·7) DALYs and 23·8% (19·8–27·7) of total overall CKD DALYs.

Definition This causes incorporates death and disability due to chronic kidney disease caused by diabetes type 2.

Total sources
Incidence 0
Prevalence 0
Remission 0
Causes of death 0
Other 150
Table 1: Total sources used in GBD 2019 estimation
What is new in GBD 2019?
  • •We assigned all CKD due to diabetes before age 20 to diabetes type 1.
  • •Excess mortality data (EMR) were modelled in MR-BRT by age and sex as a function of HAQ Index.
  • •Adjustments for alternative CKD estimating equations were applied prior to DisMod-MR. These adjustments increased estimates for stage 3 but resulted in small changes for stages 4 and 5 compared to previous rounds of GBD. The reference estimating equation is CKD-EPI.
Prevalence
Incidence
Deaths
YLLs
YLDs
DALYs
Cases
(millions)
Rate (per 100 000)
Cases
(millions)
Rate (per 100 000)
Deaths
(millions)
Rate (per 100 000)
YLLs
(millions)
Rate (per 100 000)
YLDs
(millions)
Rate (per 100 000)
DALYs
(millions)
Rate (per 100 000)
2019
Both Sexes
130
(119
to 140)
1576·3
(1448·3
to 1700·2)
2·50
(2·28
to 2·74)
30·3
(27·6
to 33·1)
0·406
(0·328
to 0·485)
5·2
(4·2
to 6·2)
8·18
(6·48
to 9·85)
99·8
(79·4
to 119·6)
1·69
(1·20
to 2·28)
20·4
(14·6
to 27·6)
9·87
(8·11
to 11·7)
120·2
(99·2
to 142·9)
Females
65·8
(60·5
to 71·0)
1539·3
(1416·0
to 1662·3)
1·23
(1·12
to 1·35)
28·1
(25·7
to 30·7)
0·201
(0·162
to 0·242)
4·6
(3·7
to 5·5)
3·82
(3·03
to 4·59)
87·5
(69·5
to 105·2)
0·883
(0·633
to 1·19)
20·3
(14·6
to 27·4)
4·70
(3·86
to 5·53)
107·8
(88·5
to 127·0)
Males
63·8
(58·5
to 69·1)
1619·2
(1487·8
to 1749·5)
1·27
(1·15
to 1·39)
32·9
(30·0
to 35·9)
0·205
(0·165
to 0·247)
5·9
(4·8
to 7·1)
4·36
(3·44
to 5·29)
113·9
(90·7
to 137·6)
0·807
(0·568
to 1·10)
20·6
(14·6
to 28·0)
5·17
(4·18
to 6·23)
134·5
(109·4
to 160·7)
Percentage change 2010-19
Both Sexes
25·5%
(24·0
to 27·0)
2·6%
(1·7
to 3·5)
37·8%
(36·3
to 39·2)
6·6%
(5·8
to 7·4)
31·3%
(23·6
to 38·4)
–0·4%
(–6·0
to 4·9)
26·6%
(18·4
to 34·3)
–1·1%
(–7·3
to 4·6)
23·2%
(19·9
to 26·6)
–2·9%
(–5·3
to –0·5)
26·0%
(19·3
to 32·4)
–1·4%
(–6·5
to 3·2)
Females
24·8%
(23·1
to 26·4)
2·0%
(1·1
to 3·0)
35·6%
(33·8
to 37·3)
5·4%
(4·4
to 6·6)
32·9%
(23·4
to 42·0)
1·0%
(–5·8
to 7·6)
28·4%
(18·6
to 38·5)
0·3%
(–7·2
to 7·7)
24·2%
(20·3
to 28·2)
–1·7%
(–4·7
to 1·1)
27·6%
(19·7
to 35·7)
–0·1%
(–6·2
to 5·9)
Males
26·2%
(24·7
to 27·9)
3·1%
(2·1
to 4·2)
39·9%
(38·4
to 41·4)
7·6%
(6·7
to 8·5)
29·7%
(20·7
to 38·5)
–1·9%
(–8·4
to 4·3)
25·1%
(15·1
to 34·6)
–2·4%
(–9·8
to 4·8)
22·0%
(18·6
to 25·6)
–4·2%
(–6·8
to –1·5)
24·6%
(16·2
to 32·7)
–2·7%
(–9·1
to 3·5)
Numbers in parentheses are 95% uncertainty intervals.
Table 2: Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths YLLs YLDs DALYs
1990 54th 85th 115th 106th
2010 37th 58th 98th 71st
2019 29th 47th 90th 61st
Table 3: Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined
Figure 1: Composition of DALYs by YLLs and constituent sequelae YLDs for both sexes combined, 2019
Figure 2: Percentage of DALYs attributable to top risk factors for both sexes combined, 2019
No Legend
Figure 3: Age-standardised DALY rates for each location by SDI, both sexes combined, 2019
Figure 4: Composition of DALYs by YLLs and YLDs, age group, and sex, 2019
No Legend
Figure 5: Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019

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