Summary There were 103 000 incident cases (95% UI 93 500–119 000), 44 600 deaths (40 400–50 100), and 948 000 (874 000–1 070 000) DALYs due to chronic lymphoid leukaemia globally in 2019.

Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (specifically chronic lymphoid leukaemia), including ICD-10 codes such as C91.1.

Total sources
Incidence 518
Prevalence 3
Remission 0
Causes of death 2742
Other 0
Table 1: Total sources used in GBD 2019 estimation
What is new in GBD 2019?
  • •New location-years of population-based cancer registry data were added.
  • •The minimum age group modelled was increased from 15–19 to 20–24 years.
  • •Mortality-to-incidence ratio models included additional data and were modified to perform more smoothing across time and age.
  • •Survival estimation was updated to use age-specific rather than all-ages survival curves, impacting age-specific prevalence and YLD estimates.
Prevalence
Incidence
Deaths
YLLs
YLDs
DALYs
Cases
(millions)
Rate (per 100 000)
Cases
(millions)
Rate (per 100 000)
Deaths
(millions)
Rate (per 100 000)
YLLs
(millions)
Rate (per 100 000)
YLDs
(millions)
Rate (per 100 000)
DALYs
(millions)
Rate (per 100 000)
2019
Both Sexes
0·607
(0·549
to 0·701)
7·4
(6·7
to 8·5)
0·103
(0·0935
to 0·119)
1·3
(1·2
to 1·5)
0·0446
(0·0404
to 0·0501)
0·6
(0·5
to 0·6)
0·871
(0·806
to 0·975)
10·7
(9·9
to 12·0)
0·0774
(0·0552
to 0·101)
1·0
(0·7
to 1·2)
0·948
(0·874
to 1·07)
11·7
(10·7
to 13·1)
Females
0·275
(0·245
to 0·321)
6·3
(5·6
to 7·4)
0·0482
(0·0428
to 0·0552)
1·1
(1·0
to 1·3)
0·0223
(0·0199
to 0·0251)
0·5
(0·5
to 0·6)
0·430
(0·381
to 0·491)
9·9
(8·8
to 11·3)
0·0328
(0·0238
to 0·0433)
0·8
(0·5
to 1·0)
0·463
(0·412
to 0·528)
10·6
(9·5
to 12·1)
Males
0·331
(0·290
to 0·402)
8·6
(7·6
to 10·4)
0·0553
(0·0489
to 0·0665)
1·5
(1·3
to 1·8)
0·0223
(0·0200
to 0·0263)
0·7
(0·6
to 0·8)
0·441
(0·399
to 0·519)
11·8
(10·7
to 13·9)
0·0446
(0·0317
to 0·0595)
1·2
(0·9
to 1·6)
0·486
(0·436
to 0·572)
13·0
(11·7
to 15·3)
Percentage change 2010-19
Both Sexes
30·4%
(20·8
to 40·5)
1·5%
(–5·9
to 9·4)
28·9%
(20·0
to 38·1)
–0·9%
(–7·7
to 6·2)
26·5%
(20·6
to 32·7)
–4·3%
(–8·6
to 0·4)
22·8%
(16·0
to 30·1)
–4·0%
(–9·2
to 1·7)
29·6%
(20·1
to 40·1)
–0·1%
(–7·3
to 8·0)
23·3%
(16·6
to 30·1)
–3·7%
(–8·9
to 1·7)
Females
33·9%
(22·1
to 47·4)
5·1%
(–4·1
to 15·5)
32·5%
(21·9
to 43·9)
2·6%
(–5·4
to 11·6)
30·4%
(21·6
to 40·2)
–0·6%
(–7·3
to 6·7)
28·0%
(17·7
to 39·2)
0·5%
(–7·6
to 9·5)
32·7%
(21·5
to 44·7)
2·9%
(–5·8
to 12·3)
28·3%
(18·3
to 39·1)
0·7%
(–7·1
to 9·3)
Males
27·6%
(15·2
to 40·9)
–1·2%
(–10·6
to 9·4)
26·0%
(14·2
to 38·1)
–3·9%
(–12·6
to 5·5)
22·7%
(15·5
to 30·8)
–7·7%
(–12·9
to –1·9)
18·1%
(9·6
to 26·7)
–8·1%
(–14·2
to –1·7)
27·4%
(15·0
to 41·7)
–2·4%
(–11·5
to 8·0)
18·9%
(10·5
to 27·6)
–7·6%
(–13·7
to –0·9)
Numbers in parentheses are 95% uncertainty intervals.
Table 2: Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths YLLs YLDs DALYs
1990 154th 178th 240th 242nd
2010 132nd 164th 229th 230th
2019 125th 153rd 229th 224th
Table 3: Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined
Figure 1: Composition of DALYs by YLLs and YLDs for both sexes combined, 2019
Figure 2: Percentage of DALYs attributable to top risk factors for both sexes combined, 2019
No Legend
Figure 3: Age-standardised DALY rates for each location by SDI, both sexes combined, 2019
Figure 4: Composition of DALYs by YLLs and YLDs, age group, and sex, 2019
No Legend
Figure 5: Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019