Summary Cocaine use disorders resulted in 1·15 million (95% UI 0·933–1·43) global DALYs in 2019 and were responsible for 0·05% (0·04–0·06) of total global DALYs.

Definition Cocaine dependence is a substance-related disorder involving a dysfunctional pattern of cocaine use. Included in the GBD disease modelling were cases meeting DSM or ICD diagnostic criteria.

Total sources
Incidence 0
Prevalence 353
Remission 3
Causes of death 2585
Other 10
Table 1: Total sources used in GBD 2019 estimation
What is new in GBD 2019?
  • •Based on multiple cause of death data we reassigned a larger proportion of deaths coded as undetermined intent to suicide rather than drug use disorders as was done previously based on expert opinion. The net effect of this change was a decrease in estimates of deaths due to cocaine use disorders in locations in which there was an evident preference for assigning deaths to undetermined intent codes.
  • •Used MR-BRT to adjust estimates from studies using two alternative case definitions, those measuring cocaine use as opposed to dependence and those using direct methods such as household surveys rather than triangulating between data sources, indirect methods which are our reference because they better capture all cases in the community.
Prevalence
Incidence
Deaths
YLLs
YLDs
DALYs
Cases
(millions)
Rate (per 100 000)
Cases
(millions)
Rate (per 100 000)
Deaths
(millions)
Rate (per 100 000)
YLLs
(millions)
Rate (per 100 000)
YLDs
(millions)
Rate (per 100 000)
DALYs
(millions)
Rate (per 100 000)
2019
Both Sexes
4·13
(3·26
to 5·20)
51·7
(40·7
to 65·4)
0·311
(0·238
to 0·422)
4·1
(3·1
to 5·6)
0·0128
(0·0120
to 0·0136)
0·2
(0·1
to 0·2)
0·594
(0·555
to 0·654)
7·3
(6·8
to 8·0)
0·559
(0·341
to 0·825)
7·0
(4·3
to 10·3)
1·15
(0·933
to 1·43)
14·3
(11·5
to 17·8)
Females
1·40
(1·10
to 1·80)
35·3
(27·6
to 45·3)
0·115
(0·0868
to 0·154)
3·1
(2·3
to 4·1)
0·00352
(0·00301
to 0·00393)
0·1
(0·1
to 0·1)
0·165
(0·142
to 0·185)
4·1
(3·5
to 4·6)
0·188
(0·115
to 0·274)
4·7
(2·9
to 6·9)
0·353
(0·271
to 0·445)
8·8
(6·7
to 11·1)
Males
2·72
(2·14
to 3·43)
68·0
(53·6
to 86·1)
0·197
(0·150
to 0·267)
5·1
(3·9
to 6·9)
0·00926
(0·00888
to 0·00980)
0·2
(0·2
to 0·2)
0·429
(0·407
to 0·479)
10·5
(9·9
to 11·7)
0·371
(0·226
to 0·551)
9·3
(5·6
to 13·8)
0·800
(0·656
to 0·992)
19·7
(16·1
to 24·5)
Percentage change 2010-19
Both Sexes
1·0%
(–1·3
to 3·0)
–7·5%
(–9·8
to –5·4)
–6·8%
(–9·7
to –4·4)
–9·8%
(–12·3
to –7·1)
84·4%
(74·6
to 94·5)
61·0%
(52·4
to 69·7)
81·9%
(70·8
to 91·9)
61·9%
(51·9
to 71·1)
0·6%
(–2·1
to 2·9)
–7·7%
(–10·3
to –5·2)
30·7%
(23·0
to 41·2)
18·2%
(11·7
to 27·3)
Females
0·4%
(–2·5
to 3·2)
–8·2%
(–11·0
to –5·7)
–8·3%
(–11·5
to –5·2)
–11·6%
(–14·7
to –8·6)
117·9%
(83·8
to 147·6)
91·0%
(61·2
to 117·2)
117·0%
(83·3
to 147·6)
93·8%
(64·0
to 121·1)
–0·1%
(–3·6
to 3·3)
–8·5%
(–12·0
to –5·5)
33·6%
(20·4
to 52·1)
21·0%
(9·5
to 37·0)
Males
1·2%
(–1·5
to 3·7)
–7·2%
(–10·0
to –4·7)
–6·0%
(–9·3
to –2·7)
–8·8%
(–11·9
to –5·6)
74·2%
(65·6
to 82·5)
51·9%
(44·7
to 59·1)
71·3%
(63·6
to 80·4)
52·2%
(45·4
to 61·1)
0·9%
(–2·1
to 3·9)
–7·3%
(–10·4
to –4·4)
29·4%
(22·7
to 38·7)
16·9%
(11·1
to 25·1)
Numbers in parentheses are 95% uncertainty intervals.
Table 2: Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths YLLs YLDs DALYs
1990 202nd 197th 136th 238th
2010 185th 185th 135th 223rd
2019 171st 169th 140th 208th
Table 3: Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined
Figure 1: Composition of DALYs by YLLs and constituent sequelae YLDs for both sexes combined, 2019
Figure 2: Percentage of DALYs attributable to top risk factors for both sexes combined, 2019
No Legend
Figure 3: Age-standardised DALY rates for each location by SDI, both sexes combined, 2019
Figure 4: Composition of DALYs by YLLs and YLDs, age group, and sex, 2019
No Legend
Figure 5: Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019