Summary Dengue was responsible for 36 100 deaths (95% UI 9180–44 500) and 2·38 million (0·828–3·27) DALYs in 2019. In southeast Asia in 2019, dengue had the highest DALY burden among all neglected tropical diseases and malaria.
Definition The estimates for dengue disease represent cases of clinically apparent illness (dengue fever, dengue haemorrhagic fever, dengue shock syndrome, and resulting chronic fatigue syndrome) and death. These estimates do not represent asymptomatic dengue virus infection.
Total sources | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Incidence | 1964 | |||||||||||
Prevalence | 0 | |||||||||||
Remission | 0 | |||||||||||
Causes of death | 3432 | |||||||||||
Other | 19 | |||||||||||
Table 1:
Total sources used in GBD 2019 estimation
What is new in GBD 2019?
- •A new systematic literature review identified 52 comparisons between active and passive case detection. Input data were adjusted for under-reporting using a Bayesian meta-analysis.
- •Regional age patterns were developed to disaggregate all-age case notifications into age-specific incidence, accounting for the population structure of each location before modelling.
- •A hybrid approach was employed in which ST-GPR and a negative binomial regression using fixed effects modelled the incidence of dengue disease, enabling data reported at both subnational and national levels to influence estimates.
Prevalence
|
Incidence
|
Deaths
|
YLLs
|
YLDs
|
DALYs
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases
(millions) |
Rate (per 100 000)
|
Cases
(millions) |
Rate (per 100 000)
|
Deaths
(millions) |
Rate (per 100 000)
|
YLLs
(millions) |
Rate (per 100 000)
|
YLDs
(millions) |
Rate (per 100 000)
|
DALYs
(millions) |
Rate (per 100 000)
|
|
2019 | ||||||||||||
Both Sexes | 3·39 (2·17 to 6·04) |
44·2 (28·1 to 79·2) |
56·9 (37·1 to 101) |
740·4 (478·2 to 1323·1) |
0·0361 (0·00918 to 0·0445) |
0·5 (0·1 to 0·6) |
1·83 (0·482 to 2·32) |
25·0 (6·6 to 31·8) |
0·552 (0·279 to 1·10) |
7·2 (3·6 to 14·4) |
2·38 (0·828 to 3·27) |
32·2 (11·1 to 44·2) |
Females | 1·75 (1·07 to 3·15) |
45·9 (27·6 to 83·4) |
29·4 (18·1 to 53·0) |
769·9 (469·0 to 1392·9) |
0·0170 (0·00358 to 0·0215) |
0·4 (0·1 to 0·6) |
0·842 (0·172 to 1·08) |
23·4 (4·8 to 30·2) |
0·284 (0·140 to 0·571) |
7·5 (3·6 to 15·1) |
1·13 (0·344 to 1·55) |
30·8 (9·2 to 42·5) |
Males | 1·64 (1·06 to 2·90) |
42·5 (27·4 to 75·4) |
27·5 (18·1 to 48·3) |
712·2 (466·5 to 1256·9) |
0·0190 (0·00367 to 0·0239) |
0·5 (0·1 to 0·6) |
0·989 (0·189 to 1·28) |
26·6 (5·1 to 34·6) |
0·269 (0·138 to 0·526) |
7·0 (3·6 to 13·7) |
1·26 (0·362 to 1·73) |
33·5 (9·5 to 46·3) |
Percentage change 2010-19 | ||||||||||||
Both Sexes | 5·7% (–24·2 to 75·9) |
–3·5% (–30·8 to 60·8) |
5·6% (–24·0 to 72·5) |
–3·6% (–30·6 to 57·3) |
13·1% (–7·7 to 36·4) |
–0·4% (–18·8 to 19·8) |
–2·6% (–20·6 to 21·2) |
–10·0% (–26·8 to 12·5) |
5·7% (–23·9 to 76·0) |
–3·3% (–30·2 to 61·4) |
–0·8% (–18·0 to 27·8) |
–8·6% (–24·6 to 18·4) |
Females | 5·4% (–23·5 to 75·2) |
–4·0% (–30·3 to 60·3) |
5·3% (–23·6 to 72·7) |
–4·1% (–30·3 to 56·7) |
12·1% (–11·2 to 38·8) |
–3·1% (–23·1 to 20·4) |
–7·3% (–26·0 to 19·0) |
–15·1% (–32·3 to 10·1) |
5·3% (–23·8 to 76·2) |
–3·8% (–30·5 to 60·1) |
–4·4% (–22·7 to 25·6) |
–12·6% (–29·2 to 14·9) |
Males | 6·0% (–24·9 to 76·1) |
–3·0% (–31·2 to 61·3) |
5·9% (–24·4 to 72·6) |
–3·1% (–30·8 to 57·9) |
14·0% (–9·1 to 38·3) |
1·3% (–18·7 to 22·2) |
1·8% (–19·4 to 28·0) |
–5·4% (–25·2 to 19·0) |
6·0% (–24·8 to 75·0) |
–2·7% (–30·7 to 60·4) |
2·7% (–17·1 to 31·2) |
–4·9% (–23·4 to 21·6) |
Numbers in parentheses are 95% uncertainty intervals. |
Table 2:
Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males, 2019, with percentage change between 2010 and 2019
Deaths | YLLs | YLDs | DALYs | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1990 | 100th | 81st | 102nd | 111th | ||||||||
2010 | 104th | 89th | 99th | 120th | ||||||||
2019 | 101st | 88th | 99th | 120th | ||||||||
Table 3:
Rank among Level 3 causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined

Figure 1:
Composition of DALYs by YLLs and constituent sequelae YLDs for both sexes combined, 2019


Figure 2:
Age-standardised DALY rates for each location by SDI, both sexes combined, 2019

Figure 3:
Composition of DALYs by YLLs and YLDs, age group, and sex, 2019


Figure 4:
Age-standardised DALY rates (per 100 000) by location, both sexes combined, 2019