Summary Globally in 2019, the number of HIV-related deaths was 864 000 (95% UI 786 000–996 000) and the number of new HIV infections was 1·99 million (1·76–2·26). The majority of this burden was seen in the sub-Saharan Africa super-region, which accounted for 74·0% (71·4–76·9) of global HIV-related deaths and 64·9% (61·1–69·1) of new HIV infections in 2019.
Definition The human immunodeficiency virus (HIV) causes influenza-like symptoms during the acute period following infection, and can lead to acquired immunodeficiency syndrome (AIDS) if untreated. HIV attacks the immune system, leaving infected individuals more susceptible to opportunistic infections like tuberculosis. We do not distinguish between HIV-1 and HIV-2.
Total sources | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Incidence | 1092 | |||||||||||
Prevalence | 107 | |||||||||||
Remission | 0 | |||||||||||
Causes of death | 1311 | |||||||||||
Other | 5232 | |||||||||||
- •To estimate age-specific and sex-specific HIV incidence, prevalence, and mortality in countries in sub-Saharan Africa, we switched from using Spectrum to a new model—Estimation and Projection Package—Age-Sex Model (EPP-ASM).
- •Bias associated with the location of antenatal care (ANC) clinics was adjusted using spatial information. This adjustment was an improvement on our previous method, which imputed earlier years of prevalence data based on regional averages of the epidemic peak year.
Prevalence
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Incidence
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Deaths
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YLLs
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YLDs
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DALYs
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Cases
(millions) |
Rate (per 100 000)
|
Cases
(millions) |
Rate (per 100 000)
|
Deaths
(millions) |
Rate (per 100 000)
|
YLLs
(millions) |
Rate (per 100 000)
|
YLDs
(millions) |
Rate (per 100 000)
|
DALYs
(millions) |
Rate (per 100 000)
|
|
2019 | ||||||||||||
Both Sexes | 36·8 (35·1 to 38·9) |
454·3 (433·8 to 478·6) |
1·99 (1·76 to 2·26) |
25·2 (22·4 to 28·6) |
0·864 (0·786 to 0·996) |
10·7 (9·7 to 12·4) |
43·6 (38·4 to 51·6) |
552·0 (482·7 to 655·5) |
4·01 (2·83 to 5·40) |
49·5 (35·1 to 66·6) |
47·6 (42·6 to 55·7) |
601·5 (536·2 to 703·9) |
Females | 20·1 (19·3 to 20·9) |
497·9 (478·4 to 518·7) |
0·999 (0·862 to 1·17) |
25·7 (22·3 to 30·0) |
0·428 (0·383 to 0·502) |
10·7 (9·5 to 12·6) |
22·1 (19·1 to 26·5) |
565·9 (487·3 to 681·2) |
2·20 (1·58 to 2·94) |
54·8 (39·3 to 73·2) |
24·3 (21·4 to 28·6) |
620·7 (544·0 to 734·0) |
Males | 16·8 (15·6 to 18·4) |
412·3 (383·0 to 450·7) |
0·991 (0·878 to 1·11) |
24·8 (22·0 to 27·8) |
0·435 (0·399 to 0·500) |
10·7 (9·8 to 12·4) |
21·5 (19·2 to 25·4) |
539·0 (477·4 to 636·6) |
1·81 (1·26 to 2·49) |
44·4 (30·9 to 61·1) |
23·3 (21·1 to 27·1) |
583·3 (525·7 to 679·6) |
Percentage change 2010-19 | ||||||||||||
Both Sexes | 23·3% (19·2 to 26·7) |
9·5% (5·9 to 12·7) |
–16·1% (–22·3 to –8·1) |
–23·2% (–29·0 to –15·8) |
–36·8% (–40·0 to –32·6) |
–43·9% (–46·4 to –40·6) |
–40·5% (–43·3 to –36·7) |
–46·3% (–48·7 to –43·2) |
–1·6% (–17·6 to 12·6) |
–12·3% (–26·6 to 0·4) |
–38·5% (–41·4 to –34·7) |
–44·6% (–47·1 to –41·4) |
Females | 23·6% (19·1 to 27·4) |
10·2% (6·1 to 13·6) |
–21·1% (–27·3 to –13·3) |
–27·0% (–32·9 to –19·5) |
–42·4% (–45·2 to –38·8) |
–48·7% (–51·0 to –45·9) |
–45·4% (–47·9 to –42·1) |
–50·5% (–52·8 to –47·7) |
–2·9% (–20·4 to 13·0) |
–13·0% (–28·8 to 1·3) |
–43·1% (–45·9 to –40·0) |
–48·6% (–51·0 to –45·9) |
Males | 22·8% (18·8 to 26·8) |
8·8% (5·2 to 12·2) |
–10·4% (–17·0 to –2·0) |
–19·0% (–25·1 to –11·2) |
–30·1% (–33·6 to –25·1) |
–38·0% (–41·0 to –34·1) |
–34·6% (–37·6 to –30·1) |
–41·1% (–43·8 to –37·3) |
0·0% (–13·5 to 12·8) |
–11·2% (–23·4 to 0·1) |
–32·8% (–36·0 to –28·5) |
–39·6% (–42·3 to –35·8) |
Numbers in parentheses are 95% uncertainty intervals. |
Deaths | YLLs | YLDs | DALYs | |||||||||
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1990 | 30th | 22nd | 76th | 30th | ||||||||
2010 | 8th | 6th | 44th | 7th | ||||||||
2019 | 17th | 12th | 48th | 11th | ||||||||






