Global Burden of Disease 2019 disease, injury, and impairment summaries
These two-page summaries offer a concise overview of causes, impairments, and risk factors modeled in GBD and the health loss related to them. The summaries include a summary results statement; a definition of the disease, injury, impairment, or risk; and a brief listing of modeling updates in GBD 2019 compared to previous GBD rounds. Tables and figures display metrics for each topic. Please use the menus below to select your topic of interest. To learn more about what the summaries include, please visit these pages:
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Suggested citation: Institute for Health Metrics and Evaluation (IHME). GBD 2019 Cause and Risk Summary: [CAUSE/RISK/IMPAIRMENT NAME]. Accessed [INSERT DATE]). Seattle, USA: IHME, University of Washington, 2020.
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Summary There were 524 000 incident cases (95% UI 476 000–569 000), 229 000 deaths (211 000–243 000), and 4·39 million (4·09–4·70) DALYs due to bladder cancer globally in 2019. Definition This cause includes death and disability resulting from malignant neoplasms of the bladder, including ICD-10...Read more
Summary Blindness and vision loss resulted in 26·5 million (95% UI 17·9–37·7) global YLDs in 2019, 3·1% (2·6–3·7) of total global YLDs. Definition This impairment incorporates disability resulting from all causes of moderate and worse distance vision loss, visual acuity of less than 6/18 according...Read more
Summary Blindness and vision loss resulted in 22·6 million (95% UI 15·6–31·7) global YLDs in 2019 and was responsible for 2·6% (2·2–3·2) of total global YLDs. Definition Blindness and vision loss is a GBD cause aggregate of vision loss due to glaucoma, cataract, macular degeneration, refractive...Read more
Summary There were 348 000 incident cases (95% UI 262 000–389 000), 246 000 deaths (186 000–271 000), and 8·66 million (6·72–9·57) DALYs due to brain and central nervous system cancer globally in 2019. Definition This cause includes death and disability resulting from malignant neoplasms of the...Read more
Summary There were 2·00 million (95% UI 1·83–2·17) incident cases, 701 000 deaths (647 000–752 000), and 20·6 million (19·0–22·2) DALYs due to breast cancer globally in 2019. Among females, breast cancer was the ninth-leading Level 3 cause of death globally in 2019. Definition This cause includes...Read more
Summary Bulimia nervosa (BN) resulted in 2·07 million (95% UI 1·19–3·20) global DALYs in 2019. BN contributed to 1·6% (1·1–2·3) of DALYs for the aggregate of mental disorders. Definition BN is an eating disorder, incorporating deaths and disability from recurrent binge eating, inappropriate...Read more
Summary Childhood sexual abuse and bullying was the 14th-leading Level 2 risk factor for YLDs in 2019. This risk was responsible for 6·74 million (95% UI 3·12–11·8) or 0·8% (0·4–1·3) of global YLDs. Definition This aggregate risk incorporates attributable burden from bullying victimisation, ie,...Read more
Summary Bullying victimisation accounted for 3·74 million (95% UI 0·97–8·35) global YLDs in 2019, or 0·4% (0·1–0·9) of YLDs. It accounted for 7·1% (2·2–14·4) and 4·6% (1·1–9·6) of YLDs for anxiety disorders and major depressive disorder (MDD), respectively. Definition Bullying victimisation is the...Read more
Summary Cannabis use disorders resulted in 690 000 (95% UI 421 000–1 080 000) global YLDs in 2019 and were responsible for 0·08% (0·05–0·1) of total global YLDs. 65·7% (64·8–66·6) of global DALYs from cannabis use disorders were among males. Definition Cannabis dependence is a substance-related...Read more
Summary Cardiomyopathy and myocarditis (CMP) was responsible for 9·14 million (95% UI 7·86–10·0) DALYs in 2019. In 2019, there were 2·30 million (1·78–2·94) prevalent cases of CMP in males and 1·76 million (1·35–2·30) prevalent cases in females. Definition This aggregate Level 3 cause incorporates...Read more