Global Burden of Disease 2019 disease, injury, and impairment summaries
These two-page summaries offer a concise overview of causes, impairments, and risk factors modeled in GBD and the health loss related to them. The summaries include a summary results statement; a definition of the disease, injury, impairment, or risk; and a brief listing of modeling updates in GBD 2019 compared to previous GBD rounds. Tables and figures display metrics for each topic. Please use the menus below to select your topic of interest. To learn more about what the summaries include, please visit these pages:
- Learn more about GBD 2019 Disease, Injury, and Impairment Summaries
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Suggested citation: Institute for Health Metrics and Evaluation (IHME). GBD 2019 Cause and Risk Summary: [CAUSE/RISK/IMPAIRMENT NAME]. Accessed [INSERT DATE]). Seattle, USA: IHME, University of Washington, 2020.
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Summary Chronic kidney disease (CKD) was responsible for 41·5 million (95% UI 38·3–45·0) DALYs in 2019. Age-standardised DALY rates were highest in central and Andean Latin America, at 1348·1 (1203·6–1521·6) and 836·3 (704·2–981·6) per 100 000, respectively (global rate was 514·9 [474·9–558·9])...Read more
Summary There were 103 000 incident cases (95% UI 93 500–119 000), 44 600 deaths (40 400–50 100), and 948 000 (874 000–1 070 000) DALYs due to chronic lymphoid leukaemia globally in 2019. Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone...Read more
Summary There were 65 800 incident cases (95% UI 59 400–74 100), 29 900 deaths (27 000–33 500), and 1·05 million (0·924–1·19) DALYs due to chronic myeloid leukaemia globally in 2019. Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (...Read more
Summary Chronic obstructive pulmonary disease (COPD) resulted in 74·4 million (95% UI 68·2–80·2) global DALYs and 71·9% (67·9–75·4) of total chronic respiratory disease DALYs in 2019. Definition COPD is a disease characterised by persistent respiratory symptoms and airflow limitation due to airway...Read more
Summary Chronic respiratory diseases was responsible for 71·1 million (95% UI 64·7–77·0) YLLs and 32·4 million (26·1–38·5) YLDs in 2019. Chronic obstructive pulmonary disease (COPD) and asthma were the two largest contributors to global respiratory disease burden. Definition Chronic respiratory...Read more
Summary Cirrhosis and other chronic liver diseases due to alcohol use resulted in 11·2 million (95% UI 9·45–13·1) global DALYs in 2019. Definition Cirrhosis and other chronic liver diseases due to alcohol use includes conditions in which there is progressive destruction of hepatic cells and...Read more
Summary Cirrhosis and other chronic liver diseases due to hepatitis B resulted in 10·8 million (95% UI 8·99–12·7) global DALYs in 2019 and was responsible for 23·3% (19·9–26·9) of cirrhosis DALYs. Definition Cirrhosis and other chronic liver diseases due to hepatitis B includes conditions in which...Read more
Summary Cirrhosis and other chronic liver diseases due to hepatitis C resulted in 12·2 million (95% UI 10·3–14·2) global DALYs in 2019 and was responsible for 26·3% (22·9–30·5) of cirrhosis DALYs. Definition Cirrhosis and other chronic liver diseases due to hepatitis C includes conditions in which...Read more
Summary Cirrhosis and other chronic liver diseases due to other causes resulted in 8·44 million (95% UI 6·94–10·2) global DALYs in 2019. Definition This cause includes cirrhosis and other chronic liver diseases due to causes other than hepatitis B, hepatitis C, alcohol, and NAFLD. Total sources...Read more
Summary Cirrhosis and other chronic liver diseases resulted in 46·2 million (95% UI 43·0–49·6) global DALYs in 2019 and 1·8% (1·6–2·0) of global DALYs. Alcohol and hepatitis B and C contributed 24·2% (20·5–28·1), 23·3% (19·9–26·9), and 26·3% (22·9–30·5) of DALYs from cirrhosis, respectively...Read more