Global Burden of Disease 2019 disease, injury, and impairment summaries
These two-page summaries offer a concise overview of causes, impairments, and risk factors modeled in GBD and the health loss related to them. The summaries include a summary results statement; a definition of the disease, injury, impairment, or risk; and a brief listing of modeling updates in GBD 2019 compared to previous GBD rounds. Tables and figures display metrics for each topic. Please use the menus below to select your topic of interest. To learn more about what the summaries include, please visit these pages:
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Suggested citation: Institute for Health Metrics and Evaluation (IHME). GBD 2019 Cause and Risk Summary: [CAUSE/RISK/IMPAIRMENT NAME]. Accessed [INSERT DATE]). Seattle, USA: IHME, University of Washington, 2020.
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Summary Cirrhosis and other chronic liver diseases due to non-alcoholic fatty liver disease (NAFLD) resulted in 3·62 million (95% UI 2·59–4·86) global DALYs in 2019 and was responsible for 7·8% (5·6–10·5) of cirrhosis and other chronic liver disease DALYs. Definition This cause includes a range of...Read more
Summary Coal workers pneumoconiosis was responsible for 58 400 YLLs (95% UI 39 000–79 100) and 16 900 YLDs (10 700–24 800) in 2019. Coal workers pneumoconiosis was responsible for 8·2% (5·9–10·7) of overall pneumoconiosis DALYs in 2019. Definition Coal workers pneumoconiosis is a lung disease...Read more
Summary Cocaine use disorders resulted in 1·15 million (95% UI 0·933–1·43) global DALYs in 2019 and were responsible for 0·05% (0·04–0·06) of total global DALYs. Definition Cocaine dependence is a substance-related disorder involving a dysfunctional pattern of cocaine use. Included in the GBD...Read more
Summary There were 2·17 million (95% UI 2·00–2·34) incident cases, 1·09 million (1·00–1·15) deaths, and 24·3 million (22·6–25·7) DALYs due to colon and rectum cancer globally in 2019. Colon and rectum cancer was the 15th-leading Level 3 cause of death globally in 2019. Definition This cause...Read more
Summary CMNN diseases caused 10·2 million (95% UI 9·19–11·4) deaths, 669 million (593–758) DALYs, and 104 million (77·1–137) YLDs, in 2019 globally for all ages, which represented a 36·3% (29·1–42·3) decrease in deaths, a 44·4% (37·4–50·5) decrease in DALYs, and a 22·1% (18·2–26·8) increase in YLDs...Read more
Summary Conduct disorder (CD) resulted in 4·87 million (95% UI 2·74–7·62) global DALYs in 2019, equivalent to 0·2% (0·1–0·3) of DALYs. CD contributed to 3·9% (2·6–5·5) of DALYs for the aggregate of mental disorders. Definition CD occurs in those under 18 years of age and incorporates disability...Read more
Summary Conflict and terrorism was responsible for 63 000 deaths (95% UI 57 200–69 300) in 2019. Of these deaths, 47 500 (43 100–52 300) occurred in locations with low SDIs and 34 (31–37) occurred in locations with high SDIs. Definition Conflict is armed violence between states, governments, and...Read more
Summary Congenital birth defects caused 549 000 deaths (95% UI 448 000–690 000) and was the fourth-ranked Level 3 cause of under-5 DALYs in 2019. The combined global incidence was 62·9 cases (54·0–73·3) per 1000 livebirths and 50·9 million (44·3–58·7) lived with birth defects in 2019. Definition...Read more
Summary Congenital heart defects caused 217 000 deaths (95% UI 177 000–262 000) in 2019. Definition This cause includes livebirths with any heart condition present at birth, including but not limited to malformations of great vessels, congenital valvular heart disease and patent ductus arteriosus,...Read more
Summary Congenital musculoskeletal defects caused 11 200 deaths (95% UI 8020–15 900) in 2019 among all ages. 17·7 million (13·6–22·2) people were living with congenital musculoskeletal and limb anomalies in 2019, a 24·8% (21·2–29·3) increase since 1990. Definition Congenital musculoskeletal defects...Read more