Improving childhood vaccine coverage is a priority for global health, but challenging in low and middle-income countries. This study provides evidence that determinants should be approached in the context of relevant outcomes, and evidence of specific determinants that could have the greatest impact if targeted.
This study underscores that, with adequate resources and technical expertise, collecting data for quality indicators at scale in low- and middle-income countries is possible.
The protozoan Cryptosporidium is a leading cause of diarrhea morbidity and mortality in children younger than 5 years. Our findings show that the substantial short-term burden of diarrhea from Cryptosporidium infection on childhood growth and well-being is an underestimate of the true burden.