Brazil has high burdens of tuberculosis (TB) and HIV, as previously estimated for the 26 states and the Federal District, as well as high levels of inequality in social and health indicators. We improved the geographic detail of burden estimation by modelling deaths due to TB and HIV and TB case fatality ratios for the more than 5,400 municipalities in Brazil.
September 6, 2018
August 16, 2017
The effect of facility-based antiretroviral therapy programs on outpatient services in Kenya and Uganda
Considerable debate exists concerning the effects of antiretroviral therapy (ART) service scale-up on non-HIV services and overall health system performance in sub-Saharan Africa. In this study, we examined whether ART services affected trends in non-ART outpatient department visits in Kenya and Uganda.
September 20, 2016
Estimating the burden of disease attributable to injecting drug use as a risk factor for HIV, hepatitis C, and hepatitis B: findings from the Global Burden of Disease Study 2013
Previous estimates of the burden of HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) among people who inject drugs have not included estimates of the burden attributable to the consequences of past injecting. We aimed to provide these estimates as part of the Global Burden of Disease (GBD) Study 2013.
July 20, 2016
The potential to expand antiretroviral therapy by improving health facility efficiency: evidence from Kenya, Uganda, and Zambia
Since 2000, international funding for HIV has supported scaling up antiretroviral therapy (ART) in sub-Saharan Africa. However, such funding has stagnated for years, threatening the sustainability and reach of ART programs amid efforts to achieve universal treatment. Improving health system efficiencies, particularly at the facility level, is an increasingly critical avenue for extending limited resources for ART; nevertheless, the potential impact of increased facility efficiency on ART capacity remains largely unknown. Through the present study, we sought to quantify facility-level technical efficiency across countries, assess potential determinants of efficiency, and predict the potential for additional ART expansion.
July 19, 2016
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015
Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.
May 18, 2016
Little is known about survival outcomes of HIV patients on first-line antiretroviral therapy (ART) on a large-scale in India, or facility level factors that influence patient survival to guide further improvements in the ART program in India. We examined factors at the facility level in addition to patient factors that influence survival of adult HIV patients on ART in the publicly-funded ART program in a high- and a low-HIV prevalence state.
March 24, 2016
Evaluating facility-based antiretroviral therapy program effectiveness: a pilot study comparing viral load suppression and retention rates
Increased demand for antiretroviral therapy (ART) services combined with plateaued levels of development assistance for HIV/AIDS requires that national ART programs monitor program effectiveness. In this pilot study, we compared commonly utilized performance metrics of 12- and 24-month retention with rates of viral load (VL) suppression at 15 health facilities in Uganda.
March 6, 2016
To better understand the global response to HIV/AIDS, this study tracked development assistance for HIV/AIDS at a granular, program level.
December 30, 2015
Patient satisfaction and perceived quality of care: evidence from a cross-sectional national exit survey of HIV and non-HIV service users in Zambia
In this study, we report findings from exit surveys of patients receiving HIV and non-HIV services at a diverse sample of facilities across Zambia.
October 26, 2015
The clock is ticking: the rate and timeliness of antiretroviral therapy initiation from the time of treatment eligibility in Kenya
Understanding the determinants of timely antiretroviral therapy (ART) initiation is useful for HIV programs intent on developing models of care that reduce delays in treatment initiation while maintaining a high quality of care. We analyzed patient- and facility-level determinants of time to ART initiation among patients who initiated ART in Kenya.
August 14, 2015
Patients receiving antiretroviral therapy (ART) require routine monitoring to track response to treatment and assess for treatment failure. This study aims to identify gaps in monitoring practices in Kenya and Uganda.
March 27, 2015
Antiretroviral therapy (ART) guidelines were significantly changed by the World Health Organization in 2010. It is largely unknown to what extent these guidelines were adopted into clinical practice.
January 28, 2015
This report draws from the Access, Bottlenecks, Costs, and Equity (ABCE) project in Ghana, a multipronged and multicountry research collaboration focused on understanding what drives and hinders health service provision
November 11, 2014
Pushing the Pace: Progress and Challenges in Fighting Childhood Pneumonia examines recent gains in reducing child deaths from pneumonia. This report advances our understanding of the burden of childhood pneumonia and its toll within the context of the leading killers of children; global trends in funding to address pneumonia; and health system factors involved in the effective prevention, diagnosis, and treatment of pneumonia.
October 2, 2014
Health Service Provision in Kenya: Assessing Facility Capacity, Costs of Care, and Patient Perspectives
This report draws from the Access, Bottlenecks, Costs, and Equity (ABCE) project in Kenya, a multi-pronged and multi-country research collaboration focused on understanding what drives and hinders health service provision
October 2, 2014
Health Service Provision in Uganda: Assessing Facility Capacity, Costs of Care, and Patient Perspectives
This report draws from the Access, Bottlenecks, Costs, and Equity (ABCE) project in Uganda, a multi-pronged and multi-country research collaboration focused on understanding what drives and hinders health service provision.
October 2, 2014
Health Service Provision in Zambia: Assessing Facility Capacity, Costs of Care, and Patient Perspectives
This report draws from the Access, Bottlenecks, Costs, and Equity (ABCE) project in Zambia, a multi-pronged and multi-country research collaboration focused on understanding what drives and hinders health service provision.
July 21, 2014
Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether accelerated progress has occurred since the Millennium Declaration.
April 8, 2014
Financing Global Health 2013: Transition in an Age of Austerity depicts financing trends that underline the resilience of development assistance for health. This year’s updated estimates show that despite lackluster economic growth and fiscal cutbacks in many developed countries, total assistance remained steady, reaching an all-time high of $31.3 billion in 2013. While annual increases have leveled off since 2010, continued international funding is a sign of the international development community’s enduring support for global health.
March 31, 2014
This report quantifies, for the first time, the global health loss from injuries and air pollution that can be attributed to motorized road transport. It combines estimates of the global burden of road injuries based on a large pool of new data from the most information-poor regions with estimates of the health effects of pollution from vehicles.