Summary There were 153 000 incident cases (95% UI 129 000–171 000), 47 600 deaths (39 400–53 000), and 2·66 million (2·19–3·01) DALYs due to acute lymphoid leukaemia globally in 2019.
Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (specifically acute lymphoid leukaemia), including ICD-10 codes such as C91.0.
Total sources | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Incidence | 1061 | |||||||||||
Prevalence | 3 | |||||||||||
Remission | 0 | |||||||||||
Causes of death | 2872 | |||||||||||
Other | 0 | |||||||||||
Table 1:
Total sources used in GBD 2019 estimation
What is new in GBD 2019?
- •New location-years of population-based cancer registry data were added, with a focus on paediatric cancer data.
- •Mortality-to-incidence ratio models included additional data and were modified to perform more smoothing across time and age.
- •Survival estimation was updated to use age-specific rather than all-ages survival curves, impacting age-specific prevalence and YLD estimates.
Prevalence
|
Incidence
|
Deaths
|
YLLs
|
YLDs
|
DALYs
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases
(millions) |
Rate (per 100 000)
|
Cases
(millions) |
Rate (per 100 000)
|
Deaths
(millions) |
Rate (per 100 000)
|
YLLs
(millions) |
Rate (per 100 000)
|
YLDs
(millions) |
Rate (per 100 000)
|
DALYs
(millions) |
Rate (per 100 000)
|
|
2019 | ||||||||||||
Both Sexes | 0·975 (0·817 to 1·09) |
12·3 (10·3 to 13·7) |
0·153 (0·129 to 0·171) |
2·0 (1·6 to 2·2) |
0·0476 (0·0394 to 0·0530) |
0·6 (0·5 to 0·7) |
2·57 (2·10 to 2·92) |
34·8 (28·5 to 39·6) |
0·0939 (0·0642 to 0·128) |
1·2 (0·8 to 1·6) |
2·66 (2·19 to 3·01) |
36·0 (29·5 to 41·0) |
Females | 0·460 (0·350 to 0·553) |
11·5 (8·8 to 13·8) |
0·0692 (0·0528 to 0·0824) |
1·7 (1·3 to 2·1) |
0·0195 (0·0150 to 0·0233) |
0·5 (0·4 to 0·6) |
1·01 (0·765 to 1·24) |
27·8 (21·0 to 34·1) |
0·0434 (0·0278 to 0·0609) |
1·1 (0·7 to 1·5) |
1·05 (0·803 to 1·29) |
28·9 (22·0 to 35·3) |
Males | 0·515 (0·405 to 0·591) |
13·2 (10·4 to 15·1) |
0·0841 (0·0664 to 0·0962) |
2·2 (1·7 to 2·5) |
0·0282 (0·0222 to 0·0319) |
0·7 (0·6 to 0·8) |
1·56 (1·21 to 1·79) |
41·7 (32·1 to 48·1) |
0·0504 (0·0339 to 0·0699) |
1·3 (0·9 to 1·8) |
1·61 (1·25 to 1·85) |
43·0 (33·3 to 49·5) |
Percentage change 2010-19 | ||||||||||||
Both Sexes | 52·0% (33·2 to 68·1) |
31·9% (15·7 to 45·9) |
34·9% (20·6 to 49·1) |
17·6% (4·9 to 29·6) |
4·7% (–4·9 to 15·2) |
–7·0% (–15·6 to 2·4) |
–2·6% (–13·2 to 9·7) |
–9·5% (–19·4 to 2·2) |
45·4% (28·4 to 60·5) |
25·7% (11·0 to 38·9) |
–1·5% (–12·2 to 10·7) |
–8·7% (–18·7 to 2·9) |
Females | 52·6% (29·6 to 74·1) |
31·9% (11·7 to 50·0) |
36·9% (17·3 to 54·9) |
18·5% (1·4 to 33·8) |
4·6% (–9·1 to 17·0) |
–8·0% (–20·1 to 3·2) |
–3·8% (–18·8 to 10·4) |
–11·2% (–25·0 to 2·4) |
46·6% (25·0 to 66·5) |
26·1% (7·9 to 43·2) |
–2·4% (–17·5 to 11·8) |
–10·2% (–24·2 to 3·3) |
Males | 51·4% (28·5 to 72·7) |
31·8% (12·2 to 50·0) |
33·4% (16·2 to 50·9) |
16·8% (1·7 to 32·1) |
4·8% (–6·7 to 17·8) |
–6·4% (–16·3 to 4·9) |
–1·9% (–14·2 to 12·6) |
–8·4% (–20·1 to 5·1) |
44·4% (23·9 to 64·8) |
25·3% (7·6 to 42·7) |
–0·9% (–13·3 to 13·4) |
–7·7% (–19·3 to 5·7) |
Numbers in parentheses are 95% uncertainty intervals. |
Table 2:
Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes combined, females, and males in 2019, with percentage change between 2010 and 2019
Deaths | YLLs | YLDs | DALYs | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1990 | 121st | 92nd | 237th | 136th | ||||||||
2010 | 121st | 105th | 228th | 150th | ||||||||
2019 | 119th | 103rd | 225th | 150th | ||||||||
Table 3:
Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined

Figure 1:
Composition of DALYs by YLLs and YLDs for both sexes combined, 2019

Figure 2:
Percentage of DALYs attributable to top risk factors for both sexes combined, 2019


Figure 3:
Age-standardised DALY rates for each location by SDI, both sexes combined, 2019

Figure 4:
Composition of DALYs by YLLs and YLDs, age group, and sex, in 2019


Figure 5:
Age-standardised DALY rates by (per 100 000) location, both sexes combined, 2019