Summary There were 65 800 incident cases (95% UI 59 400–74 100), 29 900 deaths (27 000–33 500), and 1·05 million (0·924–1·19) DALYs due to chronic myeloid leukaemia globally in 2019.

Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow (specifically chronic myeloid leukaemia), including ICD-10 codes such as C92.1, C92.2, and C93.1.

Total sources
Incidence 1060
Prevalence 3
Remission 0
Causes of death 2854
Other 0
Table 1: Total sources used in GBD 2019 estimation
What is new in GBD 2019?
  • •New location-years of population-based cancer registry data were added, with a focus on paediatric cancer data.
  • •The minimum age group modelled was lowered from 15–19 to early neonatal (0–6 days).
  • •Mortality-to-incidence ratio models included additional data and were modified to perform more smoothing across time and age.
  • •Survival estimation was updated to use age-specific rather than all-ages survival curves, impacting age-specific prevalence and YLD estimates.
Prevalence
Incidence
Deaths
YLLs
YLDs
DALYs
Cases
(millions)
Rate (per 100 000)
Cases
(millions)
Rate (per 100 000)
Deaths
(millions)
Rate (per 100 000)
YLLs
(millions)
Rate (per 100 000)
YLDs
(millions)
Rate (per 100 000)
DALYs
(millions)
Rate (per 100 000)
2019
Both Sexes
0·252
(0·223
to 0·288)
3·2
(2·8
to 3·6)
0·0658
(0·0594
to 0·0741)
0·8
(0·7
to 0·9)
0·0299
(0·0270
to 0·0335)
0·4
(0·3
to 0·4)
1·02
(0·901
to 1·17)
12·9
(11·3
to 14·8)
0·0255
(0·0183
to 0·0336)
0·3
(0·2
to 0·4)
1·05
(0·924
to 1·19)
13·3
(11·6
to 15·2)
Females
0·123
(0·107
to 0·144)
2·9
(2·5
to 3·4)
0·0296
(0·0260
to 0·0340)
0·7
(0·6
to 0·8)
0·0117
(0·0101
to 0·0134)
0·3
(0·2
to 0·3)
0·402
(0·338
to 0·475)
10·1
(8·4
to 12·0)
0·0119
(0·00843
to 0·0158)
0·3
(0·2
to 0·4)
0·414
(0·348
to 0·487)
10·3
(8·6
to 12·3)
Males
0·129
(0·114
to 0·154)
3·5
(3·1
to 4·2)
0·0362
(0·0320
to 0·0420)
1·0
(0·9
to 1·2)
0·0183
(0·0156
to 0·0213)
0·5
(0·4
to 0·6)
0·622
(0·514
to 0·738)
16·0
(13·2
to 19·1)
0·0137
(0·00966
to 0·0182)
0·4
(0·3
to 0·5)
0·636
(0·525
to 0·754)
16·4
(13·5
to 19·5)
Percentage change 2010-19
Both Sexes
15·5%
(4·7
to 27·3)
–7·3%
(–15·8
to 2·4)
12·6%
(2·4
to 23·5)
–9·1%
(–17·0
to –0·6)
7·1%
(–3·6
to 16·2)
–12·6%
(–20·9
to –5·6)
–1·6%
(–16·8
to 12·3)
–15·0%
(–27·7
to –3·3)
14·3%
(3·7
to 25·6)
–8·3%
(–16·4
to 0·4)
–1·3%
(–16·4
to 12·6)
–14·9%
(–27·4
to –3·3)
Females
16·9%
(4·3
to 30·2)
–6·5%
(–16·6
to 3·9)
13·4%
(2·3
to 25·0)
–8·8%
(–17·7
to 0·4)
5·5%
(–5·2
to 17·3)
–13·7%
(–22·6
to –4·3)
–2·9%
(–17·1
to 13·5)
–16·1%
(–28·5
to –1·7)
15·3%
(3·4
to 28·3)
–7·8%
(–17·4
to 2·6)
–2·5%
(–16·7
to 13·7)
–15·9%
(–28·2
to –1·9)
Males
14·2%
(1·8
to 28·1)
–7·9%
(–17·4
to 3·5)
11·9%
(–0·6
to 24·7)
–9·4%
(–18·5
to 0·3)
8·1%
(–5·3
to 20·8)
–12·0%
(–21·6
to –2·9)
–0·7%
(–18·7
to 18·1)
–14·3%
(–29·1
to 0·8)
13·4%
(0·5
to 27·5)
–8·7%
(–18·6
to 2·0)
–0·5%
(–18·4
to 18·0)
–14·2%
(–28·8
to 0·6)
Numbers in parentheses are 95% uncertainty intervals.
Table 2: Global prevalence, incidence, deaths, YLLs, YLDs, and DALYs in counts and age-standardised rates for both sexes, females, and males, 2019, with percentage change between 2010 and 2019
Deaths YLLs YLDs DALYs
1990 134th 134th 258th 195th
2010 147th 147th 257th 211th
2019 143rd 144th 256th 215th
Table 3: Rank among most detailed causes for global deaths, YLLs, YLDs, and DALYs in 1990, 2010, and 2019, for both sexes combined
Figure 1: Composition of DALYs by YLLs and YLDs for both sexes combined, 2019
Figure 2: Percentage of DALYs attributable to top risk factors, 2019
No Legend
Figure 3: Age-standardised DALY rates for each location by SDI, 2019
Figure 4: Composition of DALYs by YLLs and YLDs, age group, and sex, 2019
No Legend
Figure 5: Age-standardised DALY rates (per 100 000) by location, both sexes, 2019