Biography
Gregory A. Roth, MD, MPH, is Associate Professor in the Division of Cardiology and Adjunct Associate Professor of Health Metrics Sciences a the Institute for Health Metrics and Evaluation (IHME) at the University of Washington School of Medicine. At IHME, he leads cardiovascular disease modeling for the institute’s landmark Global Burden of Disease Study.
Dr. Roth’s research focuses on global cardiovascular health surveillance, population health, and quality of care and outcomes for cardiovascular diseases such as heart failure, coronary heart disease, and pulmonary hypertension. His research has been funded by the American Heart Association, NIH (NIA, NHLBI), and the Bill & Melinda Gates Foundation.
Dr. Roth earned his bachelor’s degree and MD from Brown University and his MPH from the University of Washington. He then trained in internal medicine and cardiovascular diseases at the UW and served as an attending physician in the emergency department at Harborview Medical Center, Seattle, and as a consultant physician at Whakatane Hospital, New Zealand. He received additional training as a postdoctoral fellow with the Veterans Administration Health Services Research and Development branch. He is an attending cardiologist and echocardiographer at Harborview Medical Center, Seattle.
IHME was founded in 2007 at the University of Washington. Its mission is to deliver to the world timely, relevant, and scientifically valid evidence to improve health policy and practice.
Vaduganathan M, Mensah GA, Varieur Turco J, et al. The Global Burden of Cardiovascular Diseases and Risk: A Compass for Future Health. Journal of the American College of Cardiology. 12 December 2022. doi: 10.1016/j.jacc.2022.11.005.
GBD 2019 Indonesia Subnational Collaborators. The state of health in Indonesia’s provinces, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Global Health. 11 October 2022. doi: 10.1016/S2214-109X(22)00371-0.
Zheng P, Afshin A, Biryukov S, et al. The Burden of Proof studies: assessing the evidence of risk. Nature Medicine. 10 October 2022. doi: 10.1038/s41591-022-01973-2.
Razo C, Welgan CA, Johnson CO, et al. Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study. Nature Medicine. 10 October 2022. 10.1038/s41591-022-01974-1.
GBD 2020 Alcohol Collaborators. Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020. The Lancet. 14 July 2022. doi:10.1016/S0140-6736(22)00847-9.
Catherine O. Johnson, Alexandra S. Boon-Dooley, Nicole K. DeCleene, et al; Life Expectancy for White, Black, and Hispanic Race/Ethnicity in U.S. States: Trends and Disparities, 1990 to 2019. Ann Intern Med. [Epub 28 June 2022]. doi:10.7326/M21-3956.
GBD 2019 Adolescent Mortality Collaborators. Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 30 October 2021. doi: 10.1016/S0140-6736(21)01546-4.
GBD 2019 Police Violence US Subnational Collaborators. Fatal police violence by race and state in the USA, 1980-2019: a network meta-regression. The Lancet. 30 September 2021. doi: 10.016/S0140-6736(21)01609-3
GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Neurology. 3 September 2021. doi: 10.1016/S1474-4422(21)00252-0.
Dieleman JL, Murray CJL, Chen C, Crosby SW, Liu A, McCracken D, Pollock IA, Sahu M, Tsakalos G, Dwyer-Lindgren L, Haakenstad A, Mokdad AH, Roth GA, Scott KW. US Health Care Spending by Race and Ethnicity, 2002-2016. JAMA. 17 August 2021. doi: 10.1001/jama.2021.9937.
India State-Level Disease Burden Initiative Neurological Disorders Collaborators. The burden of neurological disorders across the states of India: the Global Burden of Disease Study 1990–2019. The Lancet Global Health. 13 July 2021. doi:10.1016/S2214-109X(21)00164-9.
GA Roth, S Emmons-Bell, HM Alger, et al. Trends in Patient Characteristics and COVID-19 In-Hospital Mortality in the United States During the COVID-19 Pandemic. JAMA Netw Open. 3 May 2021. doi: 10.1001/jamanetworkopen.2021.8828.
Roth GA, Mensah GA, Johnson CO, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019. Journal of the American College of Cardiology. 9 December 2020. doi: 10.1016/j.jacc.2020.11.010.
GBD 2017 US Neurological Disorders Collaborators. Burden of Neurological Disorders Across the US From 1990-2017. JAMA Neurology. 2 November 2020. doi: 10.1001/jamaneurol.2020.4152.
Nascimento BR, Brant LCC, Yadgir S, Oliveira GMM, Roth G, Glenn SD, Mooney M, Naghavi M, Passos VMA, Duncan BB, Silva DAS, Malta DC, Ribeiro ALP. Trends in prevalence, mortality, and morbidity associated with high systolic blood pressure in Brazil from 1990 to 2017: estimates from the “Global Burden of Disease 2017” (GBD 2017) study. Population Health Metrics. 30 September 2020. doi:10.1186/s12963-020-00218-z.
Ali S, Misganaw A, Worku A, Destaw Z, Negash L, Bekele A, Briant PS, Johnson CO, Alam T, Odell C, Roth GA, Naghavi M, Abate E, Mirkuzie AH. The burden of cardiovascular diseases in Ethiopia from 1990 to 2017: evidence from the Global Burden of Disease Study. International Health. 18 September 2020. doi:
Flor LS, Wilson S, Bhatt P, et al. Community-based interventions for detection and management of diabetes and hypertension in underserved communities: a mixed-methods evaluation in Brazil, India, South Africa and the USA. BMJ Global Health. 15 April 2020. doi:10.1136/ bmjgh-2019-001959.
Yadgir S, Johnson CO, Aboyans V, et al. Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990-2017. Circulation. 29 March 2020. doi: 10.1161/CIRCULATIONAHA.119.043391.
Zimmerman MS, Smith AGC, Sable CA, et al. Global, regional, and national burden of congenital heart disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet Child & Adolescent Health. 21 January 2020; doi: 10.1016/S2352-4642(19)30402-X.
The WHO CVD Risk Chart Working Group. World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions. The Lancet Global Health. 2 September 2019. doi:10.1016/S2214-109X(19)30318-3.
GBD 2017 Child and Adolescent Health Collaborators. Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017. JAMA Pediatrics. 29 April 2019. doi:10.1001/jamapediatrics.2019.0337.
GBD 2017 Diet Collaborators. Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2 April 2019. doi: 10.1016/S0140-6736(19)30041-8.
GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 14 March 2019. doi:10.1016/S1474-4422(18)30499-X.
GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology. 11 March 2019. doi:10.1016/S1474-4422(19)30034-1.
GBD 2016 Lifetime Risk of Stroke Collaborators. Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016. The New England Journal of Medicine. 19 Dec 2018. doi:10.1056/NEJMoa1804492.
GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 8 Nov 2018;392:1736-88. doi: http://dx.doi.org/10.1016/S0140-6736(18)32203-7.
GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 8 Nov 2018;392:1923-94. doi: http://dx.doi.org/10.1016/S0140-6736(18)32225-6.
India State-Level Disease Burden Initiative CVD Collaborators. The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990–2016. The Lancet Global Health. 12 September 2018. doi:10.1016/S2214-109X(18)30407-8.
GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 23 Aug 2018. doi:10.1016/S0140-6736(18)31310-2
GBD 2016 Healthcare Access and Quality Collaborators. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. The Lancet. 23 May 2018.
US Burden of Disease Collaborators. The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA. 10 April 2018; 319(14):1-33. doi:10.1001/jama.2018.0158
Duber HC, McNellan CR, Wollum A, et al. Public knowledge of cardiovascular disease and response to acute cardiac events in three cities in China and India. Heart 2018;104:67-72.
India State-level Disease Burden Initiative Collaborators. Nations within a nation: variations in epidemiological transition across the states of India, 1990–2016 in the Global Burden of Disease Study. The Lancet. 13 Nov 2017. doi: http://dx.doi.org/10.1016/S0140-6736(17)32804-0
GBD 2016 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1151–210.
GBD 2016 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1260-344.
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390; 1211–59.
GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1345-1422.
GBD 2016 Mortality Collaborators. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 14 Sept 2017: 390;1084–1150.
GBD 2016 SDG Collaborators. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. The Lancet. 12 Sept 2017: 390; 1423–59.
Watkins DA, Johnson CO, Colquhoun SM, et al. Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015. The New England Journal of Medicine. 23 Aug 2017; 377(8):713-22. doi: 10.1056/NEJMoa1603693
GBD 2015 Eastern Mediterranean Region Collaborators. Danger ahead: the burden of diseases, injuries, and risk factors 3 in the Eastern Mediterranean Region, 1990–2015. International Journal of Public Health. 7 Aug 2017.
GBD 2015 Eastern Mediterranean Region Collaborators. Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990–2015: findings from the Global Burden of Disease 2015 study. International Journal of Public Health. 7 Aug 2017.
Nomura S, Sakamoto H, Glenn S, et al. Population health and regional variations of disease burden in Japan, 1990–2015: a systematic subnational analysis for the Global Burden of Disease Study 2015. The Lancet. 19 Jul 2017 doi: http://dx.doi.org/10.1016/S0140-6736(17)31544-1.
Global, regional, and national burden of cardiovascular diseases for 10 causes, 1990 to 2015. Journal of the American College of Cardiology. 17 May 2017. http://dx.doi.org/10.1016/j.jacc.2017.04.052.
Roth GA, Dwyer-Lindgren, Bertozzi-Villa A, Stubbs RW, Morozoff C, Naghavi M, Mokdad AH, Murray CJL. Trends and patterns of geographic variation in cardiovascular mortality among US counties, 1980–2014. JAMA. 2017 May 16.
Carlson S, Duber HC, Achan J, Ikilezi G, Mokdad AH, Stergachis A, Wollum A, Bukhman G, Roth GA. Capacity for diagnosis and treatment of heart failure in sub-Saharan Africa. Heart. 2017 May 10. doi: 10.1136/heartjnl-2016-310913.
Thomas B, Matsushita K, Abate KH, et al. Global cardiovascular and renal outcomes of reduced GFR. JASN. 2017 Apr 13. doi: 10.1681/ASN.2016050562.
GBD 2015 Tobacco Collaborators. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015. The Lancet. 2017 April 7;14:48. http://dx.doi.org/10.1016/S0140-6736(17)30819-X
Forouzanfar MH, Liu P, Roth GA, et al. Global burden of hypertension and systolic blood pressure of at least 110 to 115 mmHg, 1990–2015. JAMA. 2017 Jan 10;317(2):165-182. doi:10.1001/jama.2016.19043.
Benziger CP, Roth GA, Moran AE. The Global Burden of Disease study and the preventable burden of NCD. Global Heart. 2016 Dec 8; 11(4):393-397. doi: 10.1016/j.gheart.2016.10.024.
GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 7; 388:1659–1724.
GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 7; 388:1545–1602.
GBD 2015 Child Mortality Collaborators. Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 7; 388:1725–1774.
GBD 2015 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 7; 388:1603–1658.
GBD 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 7; 388:1459–1544.
Lim SS, Allen K, Bhutta ZA, et al. Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet. 2016 Sep 21. doi: 10.1016/S0140-6736(16)31467-2.
Mokdad AH, Forouzanfar MH, Daoud F, et al. Health in times of uncertainty in the Eastern Mediterranean Region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet Global Health. 2016 Aug. doi: 10.1016/S2214-109X(16)30168-1.
Gabert R, Thomson B, Gakidou E, Roth G. Identifying High-Risk Neighborhoods Using Electronic Medical Records: A Population-Based Approach for Targeting Diabetes Prevention and Treatment Interventions. PLoS ONE. 2016 27 July; 11(7): e0159227. doi: 10.1371/journal.pone.0159227.
Feigin VL, Norrving B, George MG, Foltz JL, Roth GA, Mensah GA. Prevention of stroke: a strategic global imperative. Nature Reviews Neurology. 2016 22 July. doi:10.1038/nrneurol.2016.107.
Feigin VL, Roth GA, Naghavi M, et al. Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet Neurology. 2016 Jun 9. doi: 10.1016/S1474-4422(16)30073-4.
Kyu HH, Pinho C, Wagner JA, et al. Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: Findings from the Global Burden of Disease 2013 study. JAMA Pediatrics. 2015 Jan 25. doi: 10.1001/jamapediatrics.2015.4276.
Krishnamurthi RV, deVeber G, Feigin VL, et al. Stroke prevalence, mortality and disability-adjusted life years in children and youth aged 0–19 years: Data from the global and regional burden of stroke 2013. Neuroepidemiology. 2015 Oct 28;45:177-189. doi: 10.1159/000441087.
Krishnamurthi RV, Moran AE, Feigin VL, et al. Stroke prevalence, mortality and disability-adjusted life years in adults aged 20–64 years in 1990–2013: Data from the Global Burden of Disease 2013 study. Neuroepidemiology. 2015;45:190-202. doi:10.1159/000441098.
Feigin VL, Krishnamurthi RV, Parmar P, et al. Update on the global burden of ischemic and hemorrhagic stroke in 1990–2013: the GBD 2013 study. Neuroepidemiology. 2015 Oct 28;45:161-176. doi:10.1159/000441085.
Feigin VL, Mensah GA, Norrving B, Murray CJL, Roth GA, GBD 2013 Stroke Panel Experts Group. Atlas of the global burden of stroke (1990–2013): the GBD 2013 study. Neuroepidemiology. 2015 Oct 28;45:230-236. doi: 10.1159/000441106.
Barker-Collo S, Bennett DA, Krishnamurthi RV, Parmar P, Feigin VL, Naghavi M, Forouzanfar MH, Johnson CO, Nguyen G, Mensah GA, Vos T, Murray CJL, Roth GA, GBD 2013 Writing Group and GBD 2013 Stroke Panel Experts Group. Sex differences in stroke incidence, prevalence, mortality and disability-adjusted life years: Results from the Global Burden of Disease study 2013. Neuroepidemiology. 2015 Oct 28;45:203-214. doi:10.1159/000441103.
Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, Murray CJL. Global and regional patterns in cardiovascular mortality from 1990 to 2013. Circulation. 2015 Oct 27;132:1667-1678.
Roth GA, Johnson CO, Nguyen G, Naghavi M, Feigin VL, Murray CJL, Forouzanfar MH, Vos T. Methods for estimating the global burden of cerebrovascular diseases. Neuroepidemiology. 2015 Oct 18;45:146-151. doi: 10.1159/000441083.
Roth GA, Nguyen G, Forouzanfar MH, Mokdad AH, Naghavi M, Murray CJL. Estimates of global and regional premature cardiovascular mortality in 2025. Circulation. 2015 Sep 25; 132:1270-1282. doi: 10.1161/CIRCULATIONAHA.115.016021.
Murray CJL, Barber RM, Foreman KJ, et al. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition. The Lancet. 2015 Aug 27. doi: 10.1016/S0140-6736(15)61340-X.
Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet. 2015 June 8. doi: 10.1016/S0140-6736(15)60692-4.
Feigin VL, Krishnamurthi R, Bhattacharjee R, et al. New strategy to reduce the global burden of stroke. Stroke. 2015 April 16; 46. doi: 10.1161/STROKEAHA.115.008222.
Roth GA, Forouzanfar MH, Moran AE, Barber R, Nguyen G, Feigin VL, Naghavi M, Mensah GA, Murray CJL. Demographic and epidemiologic drivers of global cardiovascular mortality. The New England Journal of Medicine. 2015 Apr 2; 372:1333-1341. doi: 10.1056/NEJMoa1406656.
Mensah GA, Roth GA, Sampson UKA, Moran AE, Feigin VL, Forouzanfar MH, Naghavi M, Murray CJL. Mortality from cardiovascular diseases in sub-Saharan Africa, 1990-2013: a systematic analysis of data from the Global Burden of Disease study 2013: cardiovascular topic. Cardiovascular Journal Africa. 2015 Apr. doi: 10.5830/CVJA-2015-036.
Naghavi M, Wang H, Lozano R, et al. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet. 2014 Dec 17. doi: 10.1016/S0140-6736(14)61682-2.
Moran AE, Forouzanfar MH, Roth G, Mensah GA, Ezzati M, Flaxman A, Murray CJL, Naghavi M. The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Disease 2010 Study. Circulation. 2014 Feb 26. doi: 10.1161/CIRCULATIONAHA.113.004046.
