The Global Research on Antimicrobial Resistance (GRAM) Findings Launch

Published February 4, 2022

4 years, 471 million individual records or isolates, and 7585 study-location-years' worth of data have led to the most comprehensive analysis of the burden of AMR ever undertaken. For the first time, evidence shows that AMR is a leading cause of death globally, with new estimates highlighting the scale of the global health threat.

The GRAM report was published by The Lancet in January, 2022 and we presented the findings, including:

  • Exploring these compelling new findings on the global burden of AMR and regional patterns and trends for over 88 pathogen-drug combinations
  • Celebrating the global collaboration and 100’s of data partnerships that made this study possible
  • Considering how data can be harnessed to support governments, health systems and civil society to act and reduce the human-cost of AMR
  • Identifying immediate actions that can help countries around the world protect their health systems against the threat of AMR


  • Professor Chris Murray, Director of the Institute for Health Metrics and Evaluation
  • Dame Sally Davies, UK Special Envoy on AMR
  • Dr Hanan Balkhy, Assistant Director General for Antimicrobial Resistance, World Health Organization
  • Dr Richard Horton, Editor-in-Chief of The Lancet

The GRAM project is a collaboration led by the Institute for Health Metrics and Evaluation and the University of Oxford and was funded by the Fleming Fund, the Bill & Melinda Gates Foundation and Wellcome Trust.