ABSTRACT
In Ethiopia there is no complete registration system to measure disease burden and risk factors accurately. In this study, the 2015 Global Burden of Diseases, Injuries, and Risk Factors (GBD) data were used to analyze the incidence, prevalence, and mortality rates of malaria in Ethiopia over the last 25 years.
METHODS
GBD 2015 used verbal autopsy surveys, reports, and published scientific articles to estimate the burden of malaria in Ethiopia. Age- and gender-specific causes of death for malaria were estimated using cause of death ensemble modeling.
RESULTS
The number of new cases of malaria declined from 2.8 million [95% uncertainty interval (UI) 1.4–4.5 million] in 1990 to 621,345 (95% UI 462,230–797,442) in 2015. Malaria caused an estimated 30,323 deaths (95% UI 11,533.3–61,215.3) in 1990 and 1,561 deaths (95% UI 752.8–2,660.5) in 2015, a 94.8% reduction over the 25 years. Age-standardized mortality rate of malaria has declined by 96.5% between 1990 and 2015 with an annual rate of change of 13.4%. Age-standardized malaria incidence rate among all ages and gender declined by 88.7% between 1990 and 2015. The number of disability-adjusted life years lost (DALY) due to malaria decreased from 2.2 million (95% UI 0.76–4.7 million) in 1990 to 0.18 million (95% UI 0.12–0.26 million) in 2015, with a total reduction of 91.7%. Similarly, age-standardized DALY rate declined by 94.8% during the same period.
CONCLUSIONS
Ethiopia has achieved the 50% reduction target for malaria of the Millennium Development Goals. The country should strengthen its malaria control and treatment strategies to achieve the Sustainable Development Goals.
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Citation
Deribew A, Dejene T, Kebede B, Tessema GA, Melaku YA, Misganaw A, Gebre T, Hailu A, Biadgilign S, Amerbir A, Yirsaw BD, Abajobir AA, Shafi O, Abera SF, Negussu N, Mengistu B, Tadesse Z, Sileshi M, Cromwell E, Glenn SD, Deribe K, Stanaway JD. Incidence, prevalence and mortality rates of malaria in Ethiopia from 1990 to 2015: analysis of the global burden of diseases 2015. Malaria Journal. 2017 Jul 4;16:271. doi: 10.1186/s12936-017-1919-4.