Global Burden of Disease 2019 disease, injury, and impairment summaries
These two-page summaries offer a concise overview of causes, impairments, and risk factors modeled in GBD and the health loss related to them. The summaries include a summary results statement; a definition of the disease, injury, impairment, or risk; and a brief listing of modeling updates in GBD 2019 compared to previous GBD rounds. Tables and figures display metrics for each topic. Please use the menus below to select your topic of interest. To learn more about what the summaries include, please visit these pages:
Suggested citation: Institute for Health Metrics and Evaluation (IHME). GBD 2019 Cause and Risk Summary: [CAUSE/RISK/IMPAIRMENT NAME]. Accessed [INSERT DATE]). Seattle, USA: IHME, University of Washington, 2020.
Summary Globally, acne vulgaris was responsible for 4·96 million (95% UI 2·98–7·85) DALYs in 2019. Of these, 3·52 million (2·11–5·64) DALYs occurred in those ages 15–49 years old. Definition Acne vulgaris (or acne) is a chronic inflammatory disease of the pilosebaceous unit associated with an...
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Summary 722 000 cases (95% UI 595 000–878 000) of acute glomerulonephritis occurred in 2019, resulting in 10 500 deaths (7200–12 200) and 307 000 global DALYs (204 000–363 000). Definition This Level 3 cause incorporates death and disability resulting from acute episodes of inflammation and injury...
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Summary Acute hepatitis A resulted in 2·35 million (95% UI 1·70–3·09) global DALYs in 2019 and was responsible for 53·9% (42·9–63·6) of acute hepatitis DALYs. Definition Hepatitis A is a viral infection that affects the liver. It is transmitted by faeco-oral route. Total sources Incidence 0...
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Summary Acute hepatitis B resulted in 1·61 million (95% UI 1·17–2·21) global DALYs in 2019 and was responsible for 37·2% (27·8–47·4) of acute hepatitis DALYs. Definition Hepatitis B is a viral infection of the liver. It can be transmitted during medical procedures, through unsafe injecting,...
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Summary Acute hepatitis C resulted in 253 000 global DALYs (95% UI 145 000–375 000) in 2019 and was responsible for 5·8% (3·4–8·8) of acute hepatitis DALYs. Definition Hepatitis C is a viral infection of the liver. It is transmitted through injecting needles and during medical procedures. Total...
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Summary Acute hepatitis E resulted in 131 000 global DALYs (95% UI 84 600–191 000) in 2019 and was responsible for 3·0% (2·1–4·0) of acute hepatitis DALYs. Definition Hepatitis E is a viral infection that affects the liver. It is transmitted by faeco-oral route. Total sources Incidence 0 Prevalence...
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Summary Acute hepatitis resulted in 4·35 million (95% UI 3·57–5·22) global DALYs in 2019. Acute hepatitis A, B, C, and E contributed 53·9% (42·9–63·6), 37·2% (27·8–47·4), 5·8% (3·4–8·8), and 3·0% (2·1–4·0) to DALYs for the acute hepatitis parent, respectively. Definition Hepatitis is a viral...
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Summary There were 153 000 incident cases (95% UI 129 000–171 000), 47 600 deaths (39 400–53 000), and 2·66 million (2·19–3·01) DALYs due to acute lymphoid leukaemia globally in 2019. Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow...
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Summary There were 124 000 incident cases (95% UI 109 000–136 000), 94 100 deaths (82 600–101 000), and 3·06 million (2·77–3·37) DALYs due to acute myeloid leukaemia globally in 2019. Definition This cause includes death and disability resulting from invasive neoplasms of the blood and bone marrow...
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Summary Adverse effects of medical treatment were responsible for 106 000 deaths (95% UI 89 100–117 000) in 2019. The age-standardised mortality rate decreased from 1·5 per 100 000 (1·3–1·7) in 2010 to 1·4 per 100 000 (1·1–1·5) in 2019. Definition Death or short-term or long-term disability...
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